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ARCN1 [transport vesicle]
Stable Identifier
R-HSA-6808717
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
transport vesicle
Synonyms
Coatomer delta subunit
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Homo sapiens)
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
Retrograde COPI vesicles bind kinesin and microtubules (Homo sapiens)
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Homo sapiens)
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Homo sapiens)
coatomer [transport vesicle] (Homo sapiens)
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
ARCN1 [transport vesicle] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48444 ARCN1
Gene Names
ARCN1, COPD
Chain
initiator methionine:, chain:2-511
Reference Genes
BioGPS Gene:372 ARCN1
COSMIC (genes):ARCN1 ARCN1
CTD Gene:372 ARCN1
dbSNP Gene:372 ARCN1
ENSEMBL:ENSG00000095139 ARCN1
ENSEMBL_homo_sapiens_GENE:ENSG00000095139.15 ARCN1
HGNC:649 ARCN1
KEGG Gene (Homo sapiens):372 ARCN1
Monarch:372 ARCN1
NCBI Gene:372 ARCN1
OMIM:600820 ARCN1
UCSC:P48444 ARCN1
Reference Transcript
RefSeq:NM_001655.4 ARCN1
RefSeq:NM_001142281.1 ARCN1
Other Identifiers
11736016_a_at
11741433_a_at
11755524_a_at
16731945
201176_PM_s_at
201176_s_at
3351533
3351537
3351538
3351539
3351540
3351541
3351543
3351544
3351546
3351549
3351550
3351551
3351552
3351553
3351554
3351555
3351556
3351557
34370_at
372
7944285
A_14_P118579
A_23_P203103
A_24_P201531
A_33_P3356216
GE61609
GO:0000139
GO:0003723
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0006886
GO:0006888
GO:0006890
GO:0008344
GO:0015031
GO:0016020
GO:0016192
GO:0021691
GO:0030126
GO:0030133
GO:0030137
GO:0030663
GO:0031410
GO:0043226
GO:0043473
GO:0048193
GO:0048856
GO:0051645
GO:0051649
HMNXSV003030790
HMNXSV003035118
ILMN_1699703
PH_hs_0002805
TC11001066.hg
X81198_at
g11863153_3p_a_at
Participates
as a component of
tetrameric coatomer complex [transport vesicle] (Homo sapiens)
Other forms of this molecule
ARCN1 [endoplasmic reticulum membrane]
ARCN1 [Golgi membrane]
ARCN1 [cytosol]
Inferred To
arcn1 [transport vesicle]
(Xenopus tropicalis)
arcn1a [transport vesicle]
(Danio rerio)
copd [transport vesicle]
(Dictyostelium discoideum)
ARCN1 [transport vesicle]
(Bos taurus)
ARCN1 [transport vesicle]
(Canis familiaris)
ARCN1 [transport vesicle]
(Gallus gallus)
ARCN1 [transport vesicle]
(Plasmodium falciparum)
ARCN1 [transport vesicle]
(Sus scrofa)
copd-1 [transport vesicle]
(Caenorhabditis elegans)
Ghost homologue of ARCN1 [transport vesicle]
(Schizosaccharomyces pombe)
RET2 [transport vesicle]
(Saccharomyces cerevisiae)
Arcn1 [transport vesicle]
(Mus musculus)
Arcn1 [transport vesicle]
(Rattus norvegicus)
deltaCOP [transport vesicle]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001646.2
,
NP_001135753.1
OpenTargets
ENSG00000095139
HPA
ENSG00000095139-ARCN1
GeneCards
P48444
Ensembl
ENST00000392859
,
ENST00000264028
,
ENSP00000264028
,
ENSP00000376599
,
ENSG00000095139
PRO
P48444
Pharos - Targets
P48444
Orphanet
24350
HMDB Protein
HMDBP08332
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
8
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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