NSF-dependent hydrolysis of ATP is required to disassociate the cis-SNARE complex, releasing the SNAREs for further rounds of membrane fusion (Mayer et al, 1996; Muller et al, 1999; Muller et al, 2002; Otto et al, 1997; Whiteheart et al, 2004; Yu et al, 1999; Zhao et al, 2012; Shah et al, 2015; reviewed in Sudhof and Rothman, 2009).
Haas, A, Mayer, A, Wickner, W
Hanson, PI, Jahn, R, Otto, H
Enos, MD, Colbert, KN, Herschlag, D, Shah, N, Weis, WI
Yu, RC, Jahn, R, Brunger, AT
Matveeva, EA, Whiteheart, SW
Südhof, TC, Rothman, JE
Whiteheart, SW, Zhao, C, Smith, EC
Schiavo, G, Rabouille, C, Newman, R, Müller, JM, Shima, DT, Shorter, J, Warren, G, Freemont, P
Warren, G, Elazar, Z, Deinhardt, K, Newman, R, Shima, DT, Shorter, J, Muller, JM, Sagiv, Y
ATP hydrolysis activity of cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane]
© 2022 Reactome
