Reactome | KRTAP2-4 [cytosol]

KRTAP2-4 [cytosol]

Stable Identifier

R-HSA-6809951

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 2-4, KRA24_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP2s [cytosol] (Homo sapiens)
        
        KRTAP2-4 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP2s [cytosol] (Homo sapiens)
        
        KRTAP2-4 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BYR9 KRTAP2-4

Gene Names

KRTAP2-4, KAP2.4, KRTAP2.4

Chain

chain:1-128

Reference Genes

BioGPS Gene:730755 KRTAP2-4

BioGPS Gene:85294 KRTAP2-4

COSMIC (genes):KRTAP2-4 KRTAP2-4

CTD Gene:730755 KRTAP2-4

CTD Gene:85294 KRTAP2-4

dbSNP Gene:730755 KRTAP2-4

dbSNP Gene:85294 KRTAP2-4

ENSEMBL:ENSG00000213417 KRTAP2-4

HGNC:18891 KRTAP2-4

Monarch:730755 KRTAP2-4

Monarch:85294 KRTAP2-4

NCBI Gene:730755 KRTAP2-4

NCBI Gene:85294 KRTAP2-4

UCSC:Q9BYR9 KRTAP2-4

Reference Transcript

Other Identifiers

11735939_at

16844588

220970_PM_s_at

220970_s_at

3756706

3756707

3756708

3756713

3756714

3756715

3756716

3756718

3756719

3756720

3756721

3756722

3756725

3756726

3756727

3756728

8015206

8015208

8015210

8015214

8019574

8019576

85294

A_23_P164405

GE517539

GO:0005515

GO:0005829

GO:0005882

GO:0045095

HMNXSV003014128

HMNXSV003030762

ILMN_1658448

PH_hs_0026930

TC17001484.hg

TC17001486.hg

g13569953_3p_s_at

Participates

as a member of

KRTAP2s [cytosol] (Homo sapiens)

Inferred To

LOC100685403 [cytosol] (Canis familiaris)

Homologues of KRTAP2-3 [cytosol] (Canis familiaris)

LOC102157302 [cytosol] (Canis familiaris)

LOC100685322 [cytosol] (Canis familiaris)

Cross References

ENSEMBL

ENSP00000517788, ENST00000394015, ENSP00000458927, ENSP00000377583, ENST00000572903, ENST00000709599

OpenTargets

ENSG00000213417

HPA

ENSG00000213417-KRTAP2-4

PRO

Q9BYR9

Pharos - Targets

Q9BYR9

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:Q9UBR2 CTSZ	9	CTSZ [specific granule lumen] (R-HSA-6801304) CTSZ [extracellular region] (R-HSA-6801569) CTSZ [ficolin-1-rich granule lumen] (R-HSA-6801318) (Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen] (R-HSA-5689431) (Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle] (R-HSA-5689727) (Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689730) CTSZ [plasma membrane] (R-HSA-2022345) CTSZ [lysosomal lumen] (R-HSA-429814) CTSZ [Golgi lumen] (R-HSA-434321)	0.556	3
UniProt:Q96EZ8 MCRS1	1	MCRS1 [nucleoplasm] (R-HSA-3321849)	0.556	3
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.556	3
UniProt:Q15077 P2RY6	1	P2RY6 [plasma membrane] (R-HSA-417924)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3

Cite Us!