Reactome | KRTAP9-2 [cytosol]

KRTAP9-2 [cytosol]

Stable Identifier

R-HSA-6809965

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 9-2, KRA92_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP9s [cytosol] (Homo sapiens)
        
        KRTAP9-2 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP9s [cytosol] (Homo sapiens)
        
        KRTAP9-2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BYQ4 KRTAP9-2

Gene Names

KRTAP9-2, KAP9.2, KRTAP9.2

Chain

chain:1-174

Reference Genes

BioGPS Gene:83899 KRTAP9-2

COSMIC (genes):KRTAP9-2 KRTAP9-2

CTD Gene:83899 KRTAP9-2

dbSNP Gene:83899 KRTAP9-2

ENSEMBL:ENSG00000239886 KRTAP9-2

HGNC:16926 KRTAP9-2

Monarch:83899 KRTAP9-2

NCBI Gene:83899 KRTAP9-2

UCSC:Q9BYQ4 KRTAP9-2

Reference Transcript

RefSeq:NM_031961.2 KRTAP9-2

Other Identifiers

11741837_x_at

16834143

233631_PM_x_at

233631_x_at

3721243

3721244

3721245

3721246

3721253

3721255

3721262

3721273

3721274

3721280

3721281

3721282

3721283

3721284

3721285

3721289

3721291

3721297

8007123

8007130

8007134

83899

A_23_P89646

A_33_P3307457

GE83291

GO:0005515

GO:0005829

GO:0005882

GO:0042802

GO:0045095

HMNXSV003024112

HMNXSV003034211

Hs.307013.0.S1_3p_at

Hs.307013.0.S1_3p_x_at

ILMN_1716822

PH_hs_0032601

TC17000504.hg

TC17000506.hg

TC17002203.hg

Participates

as a member of

KRTAP9s [cytosol] (Homo sapiens)

Inferred To

Krtap9-20 [cytosol] (Mus musculus)

Homologues of KRTAP9-2 [cytosol] (Bos taurus)

Homologues of KRTAP9-2 [cytosol] (Mus musculus)

Homologues of KRTAP9-2 [cytosol] (Sus scrofa)

Krtap9-21 [cytosol] (Mus musculus)

Krtap9-1 [cytosol] (Mus musculus)

Krtap9-5l [cytosol] (Rattus norvegicus)

LOC100517674 [cytosol] (Sus scrofa)

Krtap9-22 [cytosol] (Mus musculus)

KRTAP9-2 [cytosol] (Bos taurus)

KRTAP9-2 [cytosol] (Sus scrofa)

Krtap9-5 [cytosol] (Mus musculus)

Cross References

ENSEMBL

ENST00000572513, ENSP00000458594, ENSP00000366950, ENST00000377721

OpenTargets

ENSG00000239886

HPA

ENSG00000239886-KRTAP9-2

PRO

Q9BYQ4

Pharos - Targets

Q9BYQ4

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WUK0 DUSP23	1	PTPMT1 [mitochondrial inner membrane] (R-HSA-3446802)	0.718	6
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.718	8
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.718	13
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.556	6
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:Q96FE5 LINGO1	1	LINGO1 [plasma membrane] (R-HSA-3006563)	0.556	3
UniProt:Q99497 PARK7	7	PolyUb-Misfolded PARK7 [lysosomal lumen] (R-HSA-9659997) PolyUb-Misfolded PARK7 [cytosol] (R-HSA-9641128) Ub-Misfolded PARK7 [cytosol] (R-HSA-9641123) Misfolded PARK7 [cytosol] (R-HSA-9641100) PolyUb-Misfolded PARK7 [late endosome lumen] (R-HSA-9660005) PARK7 [nucleoplasm] (R-HSA-3900141) monoSUMO1-K130-PARK7 [nucleoplasm] (R-HSA-4085351)	0.556	3
UniProt:O43597 SPRY2	8	p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) SPRY2 [cytosol] (R-HSA-182949) SPRY2 [plasma membrane] (R-HSA-182924) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-Y55-SPRY2 [cytosol] (R-HSA-182950)	0.556	3
UniProt:Q92608 DOCK2	3	DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [cytosol] (R-HSA-200938)	0.556	3
UniProt:Q92570 NR4A3	1	NR4A3 [nucleoplasm] (R-HSA-8938004)	0.556	3
UniProt:Q86YT5 SLC13A5	1	SLC13A5 [plasma membrane] (R-HSA-433135)	0.556	3
UniProt:Q96PM5 RCHY1	2	RCHY1 [cytosol] (R-HSA-976013) RCHY1 [nucleoplasm] (R-HSA-5655134)	0.556	3
UniProt:Q15077 P2RY6	1	P2RY6 [plasma membrane] (R-HSA-417924)	0.556	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	9
UniProt:Q92504 SLC39A7	1	SLC39A7 [endoplasmic reticulum membrane] (R-HSA-442363)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:Q9Y2T1 AXIN2	4	AXIN2 [cytosol] (R-HSA-3640821) ub-AXIN2 [cytosol] (R-HSA-4641131) RibC-AXIN2 [cytosol] (R-HSA-3640842) Ub-RibC-AXIN2 [cytosol] (R-HSA-3640859)	0.556	3
UniProt:Q8TCT0 CERK	1	CERK [plasma membrane] (R-HSA-1631584)	0.556	3
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.556	3
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.556	3
UniProt:Q8N6T3 ARFGAP1	1	ARFGAP1 [cytosol] (R-HSA-200464)	0.556	3

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