Reactome | KRTAP6-1 [cytosol]

KRTAP6-1 [cytosol]

Stable Identifier

R-HSA-6810298

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 6-1, KRA61_HUMAN

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP6s [cytosol] (Homo sapiens)
        
        KRTAP6-1 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP6s [cytosol] (Homo sapiens)
        
        KRTAP6-1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q3LI64 KRTAP6-1

Gene Names

KRTAP6-1, C21orf103, KAP6.1

Chain

chain:1-71

Reference Genes

BioGPS Gene:337966 KRTAP6-1

COSMIC (genes):KRTAP6-1 KRTAP6-1

CTD Gene:337966 KRTAP6-1

dbSNP Gene:337966 KRTAP6-1

ENSEMBL:ENSG00000184724 KRTAP6-1

HGNC:18931 KRTAP6-1

Monarch:337966 KRTAP6-1

NCBI Gene:337966 KRTAP6-1

UCSC:Q3LI64 KRTAP6-1

Reference Transcript

RefSeq:NM_181602.1 KRTAP6-1

Other Identifiers

11715156_s_at

11759391_at

16924855

337966

3928560

3928561

3928562

8069852

A_33_P3364520

GO:0005515

GO:0005829

GO:0005882

GO:0031424

HMNXSV003051897

ILMN_2112942

TC21000381.hg

Participates

as a member of

KRTAP6s [cytosol] (Homo sapiens)

Inferred To

ENSRNOG00000071041 [cytosol] (Rattus norvegicus)

Krtap6-1 [cytosol] (Mus musculus)

LOC112446984 [cytosol] (Bos taurus)

Cross References

ENSEMBL

ENSP00000332690, ENST00000329122

OpenTargets

ENSG00000184724

HPA

ENSG00000184724-KRTAP6-1

PRO

Q3LI64

Pharos - Targets

Q3LI64

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.556	3
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.556	3
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [cytosol] (R-HSA-446885) TOLLIP [specific granule lumen] (R-HSA-6799719) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [azurophil granule lumen] (R-HSA-6799709)	0.556	5
UniProt:A8MTQ0 NOTO	1	NOTO [nucleoplasm] (R-HSA-9796216)	0.556	3
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.556	3
UniProt:Q9UBP5 HEY2	1	HEY2 [nucleoplasm] (R-HSA-1606745)	0.556	3
UniProt:Q13227 GPS2	1	GPS2 [nucleoplasm] (R-HSA-351642)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.556	3
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.556	3

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