Reactome | RINT1 [cytosol]

RINT1 [cytosol]

Stable Identifier

R-HSA-6810991

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

RAD50-interacting protein 1, RAD50 interactor 1, HsRINT-1, RINT-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6NUQ1 RINT1

Gene Names

RINT1

Chain

chain:1-792

Reference Genes

BioGPS Gene:60561 RINT1

COSMIC (genes):RINT1 RINT1

CTD Gene:60561 RINT1

dbSNP Gene:60561 RINT1

ENSEMBL:ENSG00000135249 RINT1

HGNC:21876 RINT1

KEGG:hsa:60561 RINT1

Monarch:60561 RINT1

NCBI Gene:60561 RINT1

OMIM:610089 RINT1

UCSC:Q6NUQ1 RINT1

Reference Transcript

RefSeq:NM_021930.5 RINT1

Other Identifiers

11719574_a_at

11719575_x_at

17050055

218598_PM_at

218598_at

243043_PM_at

243043_at

3017796

3017797

3017798

3017800

3017801

3017803

3017804

3017807

3017808

3017809

3017810

3017811

3017812

3017813

3017814

3017815

3017816

3017817

3017818

3017819

3017820

3017821

3017823

3017824

3017825

3017826

3017831

3017833

3017834

52132_at

60561

68889_at

8135323

81475_at

A_14_P117670

A_14_P134456

A_14_P134939

A_23_P59677

GE86020

GO:0005515

GO:0005737

GO:0005783

GO:0005789

GO:0005829

GO:0006888

GO:0006890

GO:0007095

GO:0015031

GO:0016020

GO:0016192

GO:0060628

GO:0070939

HMNXSV003043807

Hs.157537.0.A1_3p_at

ILMN_1784584

PH_hs_0023616

TC07000682.hg

TC07000683.hg

TC07002509.hg

g11345465_3p_at

p26440

Participates

as a component of

NBAS:RINT1:ZW10 [cytosol] (Homo sapiens)

Inferred To

Rint1 [cytosol] (Drosophila melanogaster)

Rint1 [cytosol] (Mus musculus)

Rint1 [cytosol] (Rattus norvegicus)

RINT1 [cytosol] (Bos taurus)

RINT1 [cytosol] (Canis familiaris)

RINT1 [cytosol] (Dictyostelium discoideum)

RINT1 [cytosol] (Gallus gallus)

RINT1 [cytosol] (Sus scrofa)

tip20 [cytosol] (Schizosaccharomyces pombe)

rint1 [cytosol] (Danio rerio)

rint1 [cytosol] (Xenopus tropicalis)

Ghost homologue of RINT1 [cytosol] (Caenorhabditis elegans)

TIP20 [cytosol] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_068749.3

OpenTargets

ENSG00000135249

ENSEMBL

ENSP00000257700, ENSG00000135249, ENST00000257700

HPA

ENSG00000135249-RINT1

GeneCards

RINT1

PRO

Q6NUQ1

Pharos - Targets

Q6NUQ1

GlyGen

Q6NUQ1

Interactors (32)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P2W9 STX18	1	STX18 [endoplasmic reticulum membrane] (R-HSA-2029079)	0.837	8
UniProt:Q9NZ43 USE1	1	USE1 [endoplasmic reticulum membrane] (R-HSA-2193119)	0.783	10
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.781	7
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.781	7
UniProt:Q12981 BNIP1	1	BNIP1 [endoplasmic reticulum membrane] (R-HSA-6810950)	0.725	5
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.718	6
UniProt:P40222 TXLNA	1	TXLNA [cytosol] (R-HSA-449124)	0.718	6
UniProt:Q9H2F5 EPC1	1	EPC1 [nucleoplasm] (R-HSA-3321978)	0.696	5
UniProt:Q9P2Y5 UVRAG	2	UVRAG [cytosol] (R-HSA-5668884) UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9730510)	0.669	18
UniProt:O43602 DCX	1	DCX [cytosol] (R-HSA-430060)	0.666	4
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.643	4
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:P56524 HDAC4	3	HDAC4 [nucleoplasm] (R-HSA-351581) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029)	0.556	3
UniProt:Q9UL45 BLOC1S6	1	BLOC1S6 [cytosol] (R-HSA-429816)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.556	3
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.556	3
UniProt:O43815 STRN	5	STRN [cytosol] (R-HSA-9037081) STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673902) p-11Y-STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673908) STRN(1-137)-ALK(1058-1620) fusion [cytosol] (R-HSA-9700485) STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9700467)	0.556	3
UniProt:Q9UKW4 VAV3	2	VAV3 [cytosol] (R-HSA-430152) p-Y173-VAV3 [cytosol] (R-HSA-442287)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.527	3
UniProt:P21709 EPHA1	2	p-Y599,Y605-EPHA1 [plasma membrane] (R-HSA-3928336) EPHA1 [plasma membrane] (R-HSA-211415)	0.527	2
UniProt:Q13304 GPR17	1	GPR17 [plasma membrane] (R-HSA-416429)	0.527	2
UniProt:Q8WVM8 SCFD1	1	SCFD1 [cytosol] (R-HSA-5688147)	0.527	3
UniProt:P08173 CHRM4	1	CHRM4 [plasma membrane] (R-HSA-390693)	0.527	2
UniProt:P35414 APLNR	1	APLNR [plasma membrane] (R-HSA-374259)	0.527	3
UniProt:Q9Y639 NPTN	1	NPTN [plasma membrane] (R-HSA-8856422)	0.527	2
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625)	0.527	2
UniProt:Q9H1C4 UNC93B1	4	UNC93B1 [Golgi membrane] (R-HSA-1679064) UNC93B1 [endoplasmic reticulum membrane] (R-HSA-1678930) UNC93B1 P345Pfs103 [endoplasmic reticulum membrane] (R-HSA-9628866) UNC93B1 L230Afs188 [endoplasmic reticulum membrane] (R-HSA-9628869)	0.527	2
UniProt:O15287 FANCG	2	FANCG [cytosol] (R-HSA-420788) FANCG [nucleoplasm] (R-HSA-419532)	0.488	2
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2

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