Reactome | RINT1 [cytosol]

RINT1 [cytosol]

Stable Identifier

R-HSA-6810991

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

RAD50-interacting protein 1, RAD50 interactor 1, HsRINT-1, RINT-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6NUQ1 RINT1

Gene Names

RINT1

Chain

chain:1-792

Reference Genes

BioGPS Gene:60561 RINT1

COSMIC (genes):RINT1 RINT1

CTD Gene:60561 RINT1

dbSNP Gene:60561 RINT1

ENSEMBL:ENSG00000135249 RINT1

HGNC:21876 RINT1

Monarch:60561 RINT1

NCBI Gene:60561 RINT1

OMIM:610089 RINT1

UCSC:Q6NUQ1 RINT1

Reference Transcript

RefSeq:NM_021930.5 RINT1

Other Identifiers

11719574_a_at

11719575_x_at

17050055

218598_PM_at

218598_at

243043_PM_at

243043_at

3017796

3017797

3017798

3017800

3017803

3017804

3017807

3017808

3017809

3017810

3017811

3017812

3017813

3017814

3017815

3017816

3017817

3017818

3017819

3017820

3017821

3017823

3017824

3017825

3017826

3017831

3017833

3017834

52132_at

60561

68889_at

8135323

81475_at

A_14_P117670

A_14_P134456

A_14_P134939

A_23_P59677

GE86020

GO:0005515

GO:0005737

GO:0005783

GO:0005789

GO:0005829

GO:0006888

GO:0006890

GO:0007095

GO:0015031

GO:0016020

GO:0016192

GO:0043226

GO:0060628

GO:0070939

HMNXSV003043807

Hs.157537.0.A1_3p_at

ILMN_1784584

PH_hs_0023616

TC07000682.hg

TC07000683.hg

TC07002509.hg

g11345465_3p_at

p26440

Participates

as a component of

NBAS:RINT1:ZW10 [cytosol] (Homo sapiens)

Inferred To

Rint1 [cytosol] (Drosophila melanogaster)

Rint1 [cytosol] (Mus musculus)

Rint1 [cytosol] (Rattus norvegicus)

RINT1 [cytosol] (Bos taurus)

RINT1 [cytosol] (Canis familiaris)

RINT1 [cytosol] (Dictyostelium discoideum)

RINT1 [cytosol] (Gallus gallus)

RINT1 [cytosol] (Sus scrofa)

tip20 [cytosol] (Schizosaccharomyces pombe)

rint1 [cytosol] (Danio rerio)

rint1 [cytosol] (Xenopus tropicalis)

Ghost homologue of RINT1 [cytosol] (Caenorhabditis elegans)

TIP20 [cytosol] (Saccharomyces cerevisiae)

Cross References

OpenTargets

ENSG00000135249

ENSEMBL

ENST00000257700, ENSP00000257700

HPA

ENSG00000135249-RINT1

PRO

Q6NUQ1

Pharos - Targets

Q6NUQ1

GlyGen

Q6NUQ1

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P2W9 STX18	1	STX18 [endoplasmic reticulum membrane] (R-HSA-2029079)	0.788	7
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.781	7
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.781	7
UniProt:Q9NZ43 USE1	1	USE1 [endoplasmic reticulum membrane] (R-HSA-2193119)	0.723	9
UniProt:P40222 TXLNA	1	TXLNA [cytosol] (R-HSA-449124)	0.718	6
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.718	6
UniProt:Q9H2F5 EPC1	1	EPC1 [nucleoplasm] (R-HSA-3321978)	0.696	5
UniProt:Q9P2Y5 UVRAG	2	UVRAG [cytosol] (R-HSA-5668884) UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9730510)	0.669	18
UniProt:O43602 DCX	1	DCX [cytosol] (R-HSA-430060)	0.666	4
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.643	4
UniProt:Q12981 BNIP1	1	BNIP1 [endoplasmic reticulum membrane] (R-HSA-6810950)	0.643	4
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.556	3
UniProt:O43815 STRN	5	STRN [cytosol] (R-HSA-9037081) STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673902) p-11Y-STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673908) STRN(1-137)-ALK(1058-1620) fusion [cytosol] (R-HSA-9700485) STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9700467)	0.556	3
UniProt:Q9UKW4 VAV3	2	VAV3 [cytosol] (R-HSA-430152) p-Y173-VAV3 [cytosol] (R-HSA-442287)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:Q9UL45 BLOC1S6	1	BLOC1S6 [cytosol] (R-HSA-429816)	0.556	3
UniProt:P56524 HDAC4	3	polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) HDAC4 [nucleoplasm] (R-HSA-351581)	0.556	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	5
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130)	0.527	2
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.527	3
UniProt:P08173 CHRM4	1	CHRM4 [plasma membrane] (R-HSA-390693)	0.527	2
UniProt:P35414 APLNR	1	APLNR [plasma membrane] (R-HSA-374259)	0.527	3
UniProt:P21709 EPHA1	2	p-Y599,Y605-EPHA1 [plasma membrane] (R-HSA-3928336) EPHA1 [plasma membrane] (R-HSA-211415)	0.527	2
UniProt:Q8WVM8 SCFD1	1	SCFD1 [cytosol] (R-HSA-5688147)	0.527	3
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2
UniProt:O15287 FANCG	2	FANCG [nucleoplasm] (R-HSA-419532) FANCG [cytosol] (R-HSA-420788)	0.488	2

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