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STX10 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6810999
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Syntaxin-10, Syn10
Locations in the PathwayBrowser for interactor UniProt:O75379 VAMP4
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60499 STX10
Gene Names
STX10, SYN10
Chain
initiator methionine:, chain:2-249
Reference Genes
BioGPS Gene:8677 STX10
COSMIC (genes):STX10 STX10
CTD Gene:8677 STX10
dbSNP Gene:8677 STX10
ENSEMBL:ENSG00000104915 STX10
ENSEMBL_homo_sapiens_GENE:ENSG00000104915.15 STX10
HGNC:11428 STX10
KEGG Gene (Homo sapiens):8677 STX10
Monarch:8677 STX10
NCBI Gene:8677 STX10
OMIM:603765 STX10
UCSC:O60499 STX10
Reference Transcript
RefSeq:NM_003765.2 STX10
RefSeq:NM_001271611.1 STX10
Other Identifiers
11742744_a_at
11744429_a_at
11759405_x_at
16869417
212625_PM_at
212625_at
36011_at
3852080
3852081
3852082
3852083
3852085
3852086
3852087
3852088
3852089
3852092
3852093
3852095
3852096
3852097
8034631
8677
A_23_P28084
A_23_P28090
GO:0000139
GO:0000149
GO:0005484
GO:0005515
GO:0005794
GO:0005802
GO:0005829
GO:0006886
GO:0006906
GO:0012505
GO:0015031
GO:0016020
GO:0016192
GO:0019905
GO:0031090
GO:0031201
GO:0031982
GO:0032588
GO:0032880
GO:0042147
GO:0043226
GO:0048193
GO:0048278
GO:0048471
GO:0060090
GO:0061024
HMNXSV003030878
Hs.43812.0.S1_3p_at
ILMN_1753712
PH_hs_0003179
TC19001219.hg
Participates
as an output of
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)
as a component of
STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A [trans-Golgi network membrane] (Homo sapiens)
Inferred To
SYN8 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
Homologues of STX10 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
Homologues of STX10 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
fsv1 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
Syx6 [trans-Golgi network membrane]
(Drosophila melanogaster)
tlg1 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Caenorhabditis elegans)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Gallus gallus)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Mus musculus)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Rattus norvegicus)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Sus scrofa)
STX10 [trans-Golgi network membrane]
(Bos taurus)
STX10 [trans-Golgi network membrane]
(Canis familiaris)
STX10 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
syn10 [trans-Golgi network membrane]
(Dictyostelium discoideum)
VAM7 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
TLG1 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001258540.1
,
NP_003756.1
OpenTargets
ENSG00000104915
GeneCards
O60499
HPA
ENSG00000104915-STX10
Ensembl
ENSG00000104915
,
ENSP00000466298
,
ENSP00000339350
,
ENST00000587230
,
ENST00000343587
PRO
O60499
Pharos - Targets
O60499
PDB
4DND
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54920 NAPA
1
NAPA [cytosol]
(R-HSA-264469)
0.643
3
UniProt:O15400 STX7
0.527
4
UniProt:O95183 VAMP5
0.527
3
UniProt:P0DTD8 NS7B
0.527
2
UniProt:Q86Y82 STX12
0.527
4
UniProt:O75379 VAMP4
4
VAMP4 [transport vesicle]
(R-HSA-6811023)
VAMP4 [trans-Golgi network membrane]
(R-HSA-6811021)
VAMP4 [plasma membrane]
(R-HSA-8864461)
VAMP4 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869133)
0.527
3
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