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TGOLN2 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6811008
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Trans-Golgi network integral membrane protein 2, TGON2_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
Fusion of early-endosome derived vesicles at the TGN (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
TGOLN2 [trans-Golgi network membrane] (Homo sapiens)
early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
TGOLN2 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
TGOLN2 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43493 TGOLN2
Gene Names
TGOLN2, TGN46, TGN51
Chain
signal peptide:1-21, chain:22-437
Reference Genes
COSMIC (genes):TGOLN2 O434935
dbSNP Gene:10618 O434935
ENSEMBL:ENSG00000152291 TGOLN2
Participates
as a candidate of
early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
TGOLN2 [clathrin-coated endocytic vesicle membrane]
TGOLN2 [plasma membrane]
TGOLN2 [Golgi membrane]
TGOLN2 [cytoplasmic vesicle membrane]
TGOLN2 [transport vesicle]
p-TGOLN2 [endoplasmic reticulum lumen]
TGOLN2 [endoplasmic reticulum lumen]
Inferred To
Ttgn1 [trans-Golgi network membrane]
(Rattus norvegicus)
rgn [trans-Golgi network membrane]
(Drosophila melanogaster)
TGOLN2 [trans-Golgi network membrane]
(Bos taurus)
TGOLN2 [trans-Golgi network membrane]
(Canis familiaris)
TGOLN2 [trans-Golgi network membrane]
(Gallus gallus)
TGOLN2 [trans-Golgi network membrane]
(Sus scrofa)
Tgoln1 [trans-Golgi network membrane]
(Mus musculus)
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H3P7 ACBD3
1
ACBD3 [Golgi membrane]
(R-HSA-8874981)
0.548
5
UniProt:P27986 PIK3R1
16
PIK3R1 [plasma membrane]
(R-HSA-198365)
PIK3R1 [cytosol]
(R-HSA-74789)
K63polyUb-PIK3R1 [cytosol]
(R-HSA-3080572)
PIK3R1 R574T [plasma membrane]
(R-HSA-2399540)
PIK3R1 R574I [plasma membrane]
(R-HSA-2399536)
PIK3R1 D560H [plasma membrane]
(R-HSA-2399432)
PIK3R1 N564K [plasma membrane]
(R-HSA-2399431)
PIK3R1 K459del [plasma membrane]
(R-HSA-2399554)
PIK3R1 N564D [plasma membrane]
(R-HSA-2399427)
PIK3R1 D560Y [plasma membrane]
(R-HSA-2399421)
PIK3R1 R574_T576del [plasma membrane]
(R-HSA-2399544)
PIK3R1 H450_E451del [plasma membrane]
(R-HSA-2399545)
PIK3R1 Y463_L466del [plasma membrane]
(R-HSA-2399546)
PIK3R1 K379E [plasma membrane]
(R-HSA-8944148)
PIK3R1 G376R [plasma membrane]
(R-HSA-2399717)
p-Y-PIK3R1 [cytosol]
(R-HSA-9680647)
0.536
2
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