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TGOLN2 [transport vesicle]
Stable Identifier
R-HSA-6811011
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
transport vesicle
Synonyms
Trans-Golgi network integral membrane protein 2, TGON2_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
VAMP4:early endosome-to-TGN cargo [transport vesicle] (Homo sapiens)
early endosome-to-TGN cargo [transport vesicle] (Homo sapiens)
TGOLN2 [transport vesicle] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43493 TGOLN2
Gene Names
TGOLN2, TGN46, TGN51
Chain
signal peptide:1-21, chain:22-437
Reference Genes
BioGPS Gene:10618 TGOLN2
COSMIC (genes):TGOLN2 TGOLN2
CTD Gene:10618 TGOLN2
dbSNP Gene:10618 TGOLN2
ENSEMBL:ENSG00000152291 TGOLN2
ENSEMBL_homo_sapiens_GENE:ENSG00000152291.15 TGOLN2
ENSEMBL_homo_sapiens_GENE:ENSG00000292253.1 TGOLN2
HGNC:15450 TGOLN2
KEGG Gene (Homo sapiens):10618 TGOLN2
Monarch:10618 TGOLN2
NCBI Gene:10618 TGOLN2
OMIM:603062 TGOLN2
UCSC:O43493 TGOLN2
Reference Transcript
RefSeq:NM_006464.3 TGOLN2
RefSeq:NM_001206840.1 TGOLN2
RefSeq:NM_001206841.1 TGOLN2
RefSeq:NM_001206844.1 TGOLN2
Other Identifiers
10618
11716901_s_at
11716902_a_at
11716903_a_at
11716904_s_at
11755687_x_at
1566473_3p_a_at
1566473_PM_a_at
1566473_a_at
16899619
203833_PM_s_at
203833_s_at
203834_PM_s_at
203834_s_at
212040_3p_at
212040_PM_at
212040_at
212043_PM_at
212043_at
2491521
2562200
2562201
2562202
2562203
2562204
2562205
2562209
2562210
2562211
2562212
2562213
2562214
2562215
2562216
2562217
2562218
2562220
2562221
2562222
2562224
2562226
2562228
2562230
31827_s_at
31828_r_at
31829_r_at
38993_r_at
8053388
A_23_P209933
A_24_P413988
GE81643
GE86506
GO:0005515
GO:0005634
GO:0005654
GO:0005768
GO:0005783
GO:0005788
GO:0005794
GO:0005802
GO:0005886
GO:0016020
GO:0030133
GO:0030140
GO:0030669
GO:0031410
GO:0043226
HMNXSV003044783
Hs.110771.0.S1_3p_x_at
Hs.110771.0.S2_3p_at
Hs.14894.0.S1_3p_a_at
Hs.14894.0.S1_3p_s_at
ILMN_1651735
PH_hs_0001402
PH_hs_0040170
TC02002035.hg
X94333_at
g5454115_3p_a_at
Participates
as a candidate of
early endosome-to-TGN cargo [transport vesicle] (Homo sapiens)
Other forms of this molecule
TGOLN2 [clathrin-coated endocytic vesicle membrane]
TGOLN2 [plasma membrane]
TGOLN2 [Golgi membrane]
TGOLN2 [cytoplasmic vesicle membrane]
TGOLN2 [trans-Golgi network membrane]
p-TGOLN2 [endoplasmic reticulum lumen]
TGOLN2 [endoplasmic reticulum lumen]
Inferred To
Ttgn1 [transport vesicle]
(Rattus norvegicus)
Tgoln1 [transport vesicle]
(Mus musculus)
TGOLN2 [transport vesicle]
(Bos taurus)
TGOLN2 [transport vesicle]
(Gallus gallus)
Cross References
RefSeq
NP_001193769.1
,
NP_001193770.1
,
NP_001193773.1
,
NP_006455.2
OpenTargets
ENSG00000152291
HPA
ENSG00000152291-TGOLN2
GeneCards
O43493
Ensembl
ENST00000377386
,
ENST00000398263
,
ENSP00000391190
,
ENSG00000152291
,
ENST00000409015
,
ENSP00000381312
,
ENST00000444342
,
ENSP00000387035
,
ENSP00000366603
PRO
O43493
Pharos - Targets
O43493
PDB
6YAF
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H3P7 ACBD3
1
ACBD3 [Golgi membrane]
(R-HSA-8874981)
0.548
5
UniProt:P27986 PIK3R1
16
p-Y-PIK3R1 [cytosol]
(R-HSA-9680647)
PIK3R1 G376R [plasma membrane]
(R-HSA-2399717)
PIK3R1 K379E [plasma membrane]
(R-HSA-8944148)
PIK3R1 Y463_L466del [plasma membrane]
(R-HSA-2399546)
PIK3R1 H450_E451del [plasma membrane]
(R-HSA-2399545)
PIK3R1 R574_T576del [plasma membrane]
(R-HSA-2399544)
PIK3R1 D560Y [plasma membrane]
(R-HSA-2399421)
PIK3R1 N564D [plasma membrane]
(R-HSA-2399427)
PIK3R1 K459del [plasma membrane]
(R-HSA-2399554)
PIK3R1 N564K [plasma membrane]
(R-HSA-2399431)
PIK3R1 D560H [plasma membrane]
(R-HSA-2399432)
PIK3R1 R574I [plasma membrane]
(R-HSA-2399536)
PIK3R1 R574T [plasma membrane]
(R-HSA-2399540)
K63polyUb-PIK3R1 [cytosol]
(R-HSA-3080572)
PIK3R1 [cytosol]
(R-HSA-74789)
PIK3R1 [plasma membrane]
(R-HSA-198365)
0.536
2
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