Reactome | COPI vesicle uncoating at the ER

COPI vesicle uncoating at the ER

Stable Identifier

R-HSA-6811427

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

ReviewStatus

5/5

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While the details of COPI vesicle uncoating are not fully established, interactions between components of the NRZ tethering complex and coatomer may contribute to coat depolymerization and release (Zink et al, 2009; Ren et al, 2009; Tripathi et al, 2009; reviewed in Barlowe and Fink, 2013).

Literature References

PubMed ID	Title	Journal	Year
23396477	Secretory protein biogenesis and traffic in the early secretory pathway Miller, EA, Barlowe, CK	Genetics	2013
20005805	A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1 Yip, CK, Ren, Y, Jeffrey, PD, Tripathi, A, Walz, T, Hughson, FM, Huie, D	Cell	2009
19151722	Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex Ren, Y, Jeffrey, PD, Tripathi, A, Hughson, FM	Nat. Struct. Mol. Biol.	2009
19758564	A link between ER tethering and COP-I vesicle uncoating Wenzel, D, Zink, S, Schmitt, HD, Wurm, CA	Dev. Cell	2009