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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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Cytomics
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FAQ
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Citing us
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GNB1 [cytosol]
Stable Identifier
R-HSA-6814412
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
G-protein beta-1 subunit
Icon
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to mechanical stimuli (Homo sapiens)
Response of endothelial cells to shear stress (Homo sapiens)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Homo sapiens)
ADM:CALCRL:RAMP2 binds G(s):GDP:Gbeta:Ggamma heterotrimer (Homo sapiens)
ADM:CALCLR:RAMP2:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (Homo sapiens)
ADM:CALCLR:RAMP2:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma dissociates (Homo sapiens)
ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
ADORA2B:Ade-Rib:Heterotrimeric G-protein Gs:GTP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADORA2B:Ade-Rib binds heterometric G-protein Gs (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADORA2B:Ade-Rib:GsGTP dissociates (Homo sapiens)
ADORA2B:Ade-Rib:Heterotrimeric G-protein Gs:GTP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Signal amplification (Homo sapiens)
ADP signalling through P2Y purinoceptor 1 (Homo sapiens)
Activated P2Y purinoceptor 1 binds G-protein Gq (Homo sapiens)
ADP:P2RY1:G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Dissociation of the P2Y purinoceptor 1:Gq complex (Homo sapiens)
ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gq activation by P2Y purinoceptor 1 (Homo sapiens)
ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADP:P2RY1:G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADP signalling through P2Y purinoceptor 12 (Homo sapiens)
Activated P2Y purinoceptor 12 binds G-protein Gi (Homo sapiens)
ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Dissociation of the P2Y purinoceptor 12:Gi complex (Homo sapiens)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gi activation by P2Y purinoceptor 12 (Homo sapiens)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thromboxane signalling through TP receptor (Homo sapiens)
Activated TP receptor binds G-protein G13 (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Activated TP receptor binds G-proten Gq (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Dissociation of the TP:G13 complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Dissociation of the TP:Gq complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G13 activation by TP receptor (Homo sapiens)
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gq activation by TP receptor (Homo sapiens)
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin signalling through proteinase activated receptors (PARs) (Homo sapiens)
Thrombin-activated PARs activate G12/13 (Homo sapiens)
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Homo sapiens)
G-protein G12/G13 (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs activate Gq (Homo sapiens)
Thrombin-activated PAR:Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs binds G-protein G12/13 (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs binds G-protein Gq (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs:G12/13 (active) dissociate (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Homo sapiens)
G-protein G12/G13 (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PARs:Gq (active) dissociate (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Thrombin-activated PAR:Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Prostacyclin signalling through prostacyclin receptor (Homo sapiens)
Activated prostacyclin receptor binds G-protein Gs (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Dissociation of the Prostacyclin receptor:Gs complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gs activation by prostacyclin receptor (Homo sapiens)
Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Glucagon signaling in metabolic regulation (Homo sapiens)
Glucagon:GCGR mediates GTP-GDP exchange (Homo sapiens)
G-beta:G-gamma dimer [plasma membrane] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein with G(s) alpha:GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma dimer [plasma membrane] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Adrenaline,noradrenaline inhibits insulin secretion (Homo sapiens)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Homo sapiens)
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-beta:G-gamma inhibits Adenylate cyclase (Homo sapiens)
Adenylate cyclase type V or VI: G-protein beta gamma Complex [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gi,Go Heterotrimeric G-protein complex dissociates (Homo sapiens)
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
L-type Calcium Channels close in pancreatic beta cells (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Homo sapiens)
GLP1R binds GLP1 (Homo sapiens)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GLP1R binds GLP1R agonists (Homo sapiens)
GLP1R:GLP1R agonists [plasma membrane] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GLP1R:GLP1 activates G(s) (Homo sapiens)
GLP-1:GLP-1R:Heterotrimeric G(s):GTP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G(s) complex dissociates (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Homo sapiens)
G-protein alpha releases G-protein heterotrimer from PDCL (Homo sapiens)
G-protein heterotrimer [plasma membrane] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
p-S18,S19,S20,S25-PDCL:G-protein beta 1-4:gamma complex [plasma membrane] (Homo sapiens)
G-protein beta 1-4:gamma complex [plasma membrane] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PDCL promotes formation of G-beta:G-gamma heterodimers (Homo sapiens)
p-S18,S19,S20,S25-PDCL:G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
p-S18,S19,S20,S25-PDCL:G-protein beta 1-4:gamma complex [plasma membrane] (Homo sapiens)
G-protein beta 1-4:gamma complex [plasma membrane] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PDCL releases folded G-beta from TRiC/CCT (Homo sapiens)
p-S18,S19,S20,S25-PDCL:G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Inwardly rectifying K+ channels (Homo sapiens)
G protein gated Potassium channels (Homo sapiens)
Activation of G protein gated Potassium channels (Homo sapiens)
Activation of GIRK/Kir3 Channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Association of GABA B receptor with G protein beta-gamma subunits (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Binding of Gbeta/gamma to GIRK/Kir3 channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of kainate receptors upon glutamate binding (Homo sapiens)
Presynaptic function of Kainate receptors (Homo sapiens)
Activation of GRIK3 homomer (Homo sapiens)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Kainate receptor-glutamate-Gprotein complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABA B receptor activation (Homo sapiens)
Activation of GABAB receptors (Homo sapiens)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Homo sapiens)
Activation of GIRK/Kir3 Channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Association of GABA B receptor with G protein beta-gamma subunits (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Binding of Gbeta/gamma to GIRK/Kir3 channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GABA B receptor G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
Inactive G alpha (12/13) reassociates with G beta:gamma (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Homo sapiens)
G-protein G12/G13 (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Homo sapiens)
G-protein G12/G13 (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The Ligand:GPCR:G12/13 complex dissociates (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Homo sapiens)
G-protein G12/G13 (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Homo sapiens)
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Inactive G alpha (i) reassociates with G beta:gamma (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein activation (Homo sapiens)
G-protein beta-gamma subunits rebind the alpha-GDP subunit (Homo sapiens)
G protein-GDP complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The high affinity receptor complex binds to G-protein (Homo sapiens)
G protein-GDP complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Opioid:MOR:G protein-GDP complex [plasma membrane] (Homo sapiens)
G protein-GDP complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The receptor:G-protein complex binds GTP (Homo sapiens)
Opioid:MOR:G protein-GTP complex [plasma membrane] (Homo sapiens)
G protein-GTP [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The receptor:G-protein complex dissociates (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Opioid:MOR:G protein-GTP complex [plasma membrane] (Homo sapiens)
G protein-GTP [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The receptor:G-protein complex releases GDP (Homo sapiens)
Opioid:MOR:G protein-GDP complex [plasma membrane] (Homo sapiens)
G protein-GDP complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Opsins act as GEFs for G alpha-t (Homo sapiens)
G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Opsins binds G alpha-t (Homo sapiens)
G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Inactive G alpha (q) reassociates with G beta:gamma (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
GPER1 signaling (Homo sapiens)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (active):ESTG [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (active):ESTG [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPER:Heterotrimeric G-protein Gs binds ESTG (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Inactive G alpha (s) reassociates with G beta:gamma (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G alpha (z) signalling events (Homo sapiens)
Inactive G alpha (z) reassociates with G beta:gamma (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gz-activating GPCR acts as a GEF for Gz (Homo sapiens)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Homo sapiens)
Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
The Ligand:GPCR:Gz complex dissociates (Homo sapiens)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta:gamma signalling (Homo sapiens)
G beta:gamma signalling through BTK (Homo sapiens)
BTK in PIP3:BTK:G beta-gamma complex is activated (Homo sapiens)
PIP3:Active BTK:G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PIP3:BTK:G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G beta-gamma complex and PIP3 recruit BTK to membrane (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PIP3:BTK:G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PIP3:Active BTK:G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G beta:gamma signalling through CDC42 (Homo sapiens)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G beta:gamma signalling through PI3Kgamma (Homo sapiens)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Homo sapiens)
G-protein beta-gamma:PI3K gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gbeta:gamma recruits PI3K gamma (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma:PI3K gamma [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G beta:gamma signalling through PLC beta (Homo sapiens)
Gbeta:gamma activation of PLC beta (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PLC beta-mediated PIP2 hydrolysis (Homo sapiens)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
GLP1R binds GLP1 (Homo sapiens)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
G-proteins dissociate from plasma-membrane estrogen receptors (Homo sapiens)
ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Homo sapiens)
ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Membrane estrogen receptors bind SRC (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
FZD recruits trimeric G-proteins (Homo sapiens)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Gbeta:gamma activation of PLC beta (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
PLC beta-mediated PIP2 hydrolysis (Homo sapiens)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
WNT:FZD complex promotes G-protein nucleotide exchange (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
AVP:AVPR2 Complex binds inactive heterotrimeric G(s) complex (Homo sapiens)
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Homo sapiens)
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
AVPR2:AVP:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
Heterotrimeric G(s) complex dissociates (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
G-beta:G-gamma (candidates) [plasma membrane] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
GNB1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62873 GNB1
Gene Names
GNB1
Chain
initiator methionine:, chain:2-340
Reference Genes
BioGPS Gene:2782 GNB1
COSMIC (genes):GNB1 GNB1
CTD Gene:2782 GNB1
dbSNP Gene:2782 GNB1
ENSEMBL:ENSG00000078369 GNB1
ENSEMBL_homo_sapiens_GENE:ENSG00000078369.19 GNB1
HGNC:4396 GNB1
KEGG Gene (Homo sapiens):2782 GNB1
Monarch:2782 GNB1
NCBI Gene:2782 GNB1
OMIM:139380 GNB1
UCSC:P62873 GNB1
Reference Transcript
RefSeq:XM_017001061.1 GNB1
RefSeq:NM_002074.4 GNB1
RefSeq:NM_001282539.1 GNB1
RefSeq:NM_001282538.1 GNB1
RefSeq:XM_017001059.1 GNB1
RefSeq:XM_017001060.1 GNB1
Other Identifiers
11717427_a_at
11717428_s_at
200744_PM_s_at
200744_s_at
200745_PM_s_at
200745_s_at
200746_PM_s_at
200746_s_at
2391841
2391842
2391843
2391844
2391845
2391846
2391847
2391848
2391849
2391852
2391853
2391854
2391860
2391861
2391863
2391865
2391870
2391875
2391876
2391883
2391884
2391885
2391886
2391891
2391894
2391895
2391896
2391897
2391898
2391917
2782
33341_at
7911619
A_23_P22926
A_24_P71021
GE728846
GO:0001750
GO:0003824
GO:0003924
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0005834
GO:0005886
GO:0005929
GO:0007165
GO:0007186
GO:0007191
GO:0007200
GO:0007213
GO:0007265
GO:0008283
GO:0016020
GO:0016787
GO:0023052
GO:0030159
GO:0043226
GO:0044877
GO:0045202
GO:0048856
GO:0050877
GO:0050909
GO:0051020
GO:0060041
GO:0060090
GO:0070062
GO:0071380
GO:0071870
GO:0097381
GO:1903561
HMNXSV003027323
Hs.215595.0.A1_3p_s_at
Hs.215595.0.A2_3p_s_at
ILMN_1760320
M36430_s_at
PH_hs_0023640
TC01006298.hg
X04526_at
g11321584_3p_s_at
Participates
as a member of
G-protein beta 1-4 subunit [cytosol] (Homo sapiens)
G-protein beta subunit [cytosol] (Homo sapiens)
as a candidate of
G-protein beta subunit [cytosol] (Homo sapiens)
Other forms of this molecule
GNB1 [photoreceptor disc membrane]
Unfolded GNB1 [cytosol]
Partially folded GNB1 [cytosol]
GNB1 [plasma membrane]
Inferred To
GNB1 [cytosol]
(Bos taurus)
GNB1 [cytosol]
(Canis familiaris)
GNB1 [cytosol]
(Gallus gallus)
GNB1 [cytosol]
(Sus scrofa)
gpb-1 [cytosol]
(Caenorhabditis elegans)
Gbeta76C [cytosol]
(Drosophila melanogaster)
gnb1 [cytosol]
(Xenopus tropicalis)
gnb1b [cytosol]
(Danio rerio)
Gbeta13F [cytosol]
(Drosophila melanogaster)
Homologues of GNB1 [cytosol]
(Drosophila melanogaster)
Gnb1 [cytosol]
(Rattus norvegicus)
gpbA [cytosol]
(Dictyostelium discoideum)
G-protein beta 1 subunit [cytosol]
(Mus musculus)
Cross References
RefSeq
NP_001269468.1
,
XP_016856548.1
,
XP_016856550.1
,
NP_002065.1
,
XP_016856549.1
,
NP_001269467.1
OpenTargets
ENSG00000078369
HPA
ENSG00000078369-GNB1
GeneCards
P62873
Ensembl
ENST00000703703
,
ENSP00000515432
,
ENSP00000515433
,
ENSP00000515427
,
ENSP00000515428
,
ENST00000703704
,
ENST00000703701
,
ENSP00000481878
,
ENSP00000515429
,
ENST00000610897
,
ENSP00000515445
,
ENSP00000515431
,
ENST00000703700
,
ENST00000703706
,
ENST00000703708
,
ENSP00000515438
,
ENST00000703694
,
ENST00000703696
,
ENST00000703709
,
ENST00000703693
,
ENSP00000515434
,
ENSP00000515435
,
ENST00000703702
,
ENST00000703692
,
ENSP00000515436
,
ENSP00000515437
,
ENST00000378609
,
ENSG00000078369
,
ENST00000703711
,
ENST00000703697
,
ENSP00000515443
,
ENSP00000515444
,
ENSP00000515442
,
ENSP00000367872
,
ENST00000703710
,
ENST00000703699
,
ENSP00000515440
PRO
P62873
Pharos - Targets
P62873
Orphanet
25724
HMDB Protein
HMDBP08398
PDB
8IJD
,
8GE4
,
8X2K
,
8JLZ
,
7S3I
,
7XJL
,
8THK
,
6XBJ
,
7F8V
,
7TRP
,
8HPT
,
8DWG
,
8IUL
,
6OS9
,
8XJK
,
8W8A
,
7XXH
,
8YY8
,
7SBF
,
8GDA
,
8XOF
,
8JZZ
,
7RBT
,
7F24
,
8UNR
,
7W0O
,
8IKL
,
8JLN
,
8U82
,
7F1O
,
7VDM
,
7XP5
,
7XKE
,
8J6J
,
8JHI
,
7CFM
,
8HQC
,
7YDM
,
7T2H
,
7EJ8
,
5HE2
,
8IBU
,
7EZH
,
7JVR
,
8IA8
,
7T11
,
8UNN
,
8INR
,
7L0R
,
6OT0
,
7D76
,
8KFZ
,
6X18
,
8E9W
,
8GY7
,
7BB7
,
8U4P
,
7EXD
,
7W0M
,
7EJX
,
7Y66
,
8GG7
,
6WPW
,
7XP6
,
8JR9
,
6X1A
,
7E9H
,
8GHV
,
6D9H
,
7EJK
,
8JLO
,
8FEG
,
8X79
,
8GG0
,
7XBD
,
8GUT
,
8FN1
,
7RMH
,
6M1H
,
8FX5
,
6XBL
,
9AUC
,
8IOC
,
8HQE
,
7RKN
,
7CRH
,
8T3V
,
7EZK
,
7VL8
,
7YK7
,
8IBV
,
8DZS
,
8GEI
,
8UNZ
,
8F2A
,
8JXV
,
7F8W
,
7DFL
,
7Y67
,
7X2D
,
8WC9
,
8E9X
,
8IUM
,
7EW4
,
8GG8
,
7VLA
,
6LMK
,
8F0K
,
8UNV
,
6VN7
,
8GG1
,
7X2V
,
7EVY
,
8PM2
,
8J6L
,
8IW1
,
8WC5
,
7LLL
,
8JHN
,
8HMV
,
7C2E
,
8XZH
,
8FLR
,
8SAI
,
5HE3
,
8GEJ
,
6DDF
,
7YAC
,
7TYO
,
7XTC
,
8HDO
,
7XOU
,
8JLP
,
8JD3
,
7YKD
,
7X10
,
7RG9
,
7XBW
,
7XZ6
,
7KH0
,
8IOD
,
7WJ5
,
7TYF
,
8XOG
,
7TZF
,
7VIH
,
6OMM
,
7RKX
,
7RMI
,
7TMW
,
7F9Y
,
8UO3
,
8IQ4
,
8U1U
,
8THL
,
8J6P
,
8GFV
,
8HN8
,
5UKK
,
8GEC
,
7EW0
,
8I7V
,
8DDW
,
8FLS
,
8IC0
,
8W8B
,
7S8P
,
7E2Z
,
8HDP
,
6WZG
,
7XOV
,
8U83
,
7K7L
,
7E2X
,
7VIF
,
6OIJ
,
8GE5
,
7EB2
,
7XTQ
,
8W87
,
6PB0
,
6NI3
,
8UNS
,
8SG1
,
8KGK
,
7S8L
,
8ID3
,
7EW2
,
8WPU
,
7LCI
,
8JHY
,
7V68
,
7E33
,
8UNO
,
8J18
,
8GED
,
8DDX
,
7UM5
,
8JSO
,
8IW4
,
8GDB
,
7EPT
,
7TYW
,
7VUG
,
7RGP
,
7Y27
,
8F76
,
7T96
,
9AVG
,
7F58
,
7RTB
,
8I2G
,
7VUI
,
8DPF
,
7L1V
,
7X9B
,
8GG9
,
7SF8
,
8JD5
,
8GE6
,
6WHC
,
8EIT
,
4KFM
,
7S8M
,
7TYI
,
7TYH
,
7WVW
,
8IW7
,
6LFM
,
7XT8
,
7CMU
,
8HIX
,
8XOH
,
8ID4
,
7T9N
,
8HQM
,
8DPG
,
8GGA
,
8EJC
,
8X7A
,
7W6P
,
8POK
,
8IRR
,
7WXU
,
7VUY
,
8IQ6
,
8JXW
,
7Y3G
,
8J19
,
8GDC
,
7VFX
,
7RYC
,
5UKL
,
8J6Q
,
8DZP
,
7P02
,
8F2B
,
7WZ7
,
8SL3
,
8UO0
,
8DWH
,
8U4Q
,
7F4H
,
8GG2
,
8XJL
,
7F4D
,
7WVU
,
7WY8
,
7W53
,
8T3O
,
7XXI
,
8WCA
,
8UNW
,
6GDG
,
8JII
,
7XY6
,
8J6R
,
7YON
,
8WC6
,
6N4B
,
7W56
,
6G79
,
7WUQ
,
7XT9
,
7W3Z
,
7T90
,
8G05
,
8HQN
,
7V69
,
8HJ0
,
8SZG
,
5UZ7
,
8XZI
,
7XKF
,
7CKY
,
7WY0
,
7SCG
,
7VV3
,
8U26
,
7AUE
,
8XJM
,
7CX4
,
7NA8
,
7TRQ
,
7XMR
,
8HNK
,
6KPF
,
7T6B
,
7YDP
,
8GG3
,
7WUI
,
6M1I
,
7F1S
,
7F1Q
,
7EO2
,
7X9C
,
7WCN
,
7XK2
,
7Y89
,
6UVA
,
8JLQ
,
7WU3
,
8J9N
,
7VGX
,
8JD6
,
7JHJ
,
8E3X
,
7SR8
,
7YOO
,
6P9X
,
7WU5
,
7F6G
,
8J1A
,
8IY9
,
8I7W
,
8IW9
,
8ID6
,
8E9Y
,
7F53
,
8H0P
,
8WRB
,
8IRS
,
8W8Q
,
7KI0
,
8GFW
,
7YFC
,
6UUN
,
8UO4
,
8JIL
,
8GAG
,
8I95
,
8HNL
,
7L0S
,
8GG4
,
7F0T
,
7XJJ
,
8H0Q
,
7T2G
,
7P00
,
8U84
,
9AXF
,
7TRK
,
6VCB
,
8UHB
,
8JER
,
8XOI
,
6ORV
,
7VDH
,
4PNK
,
8FLT
,
8JSP
,
7F54
,
7CFN
,
7W0N
,
7YDH
,
8U7Z
,
7XK8
,
8W88
,
7CX2
,
7LLY
,
8KH4
,
8ID8
,
7RA3
,
8E9Z
,
7W0P
,
7JV5
,
8GFX
,
8IRT
,
8GEE
,
7Y1F
,
8UNP
,
7F23
,
8UNL
,
8GDZ
,
7YAE
,
8G59
,
8SMV
,
7X5H
,
8G2Y
,
7W0L
,
8K2X
,
7RKF
,
7T10
,
8J20
,
7EJ0
,
8GE7
,
8IYH
,
8U4N
,
8FLU
,
8EMW
,
7LD3
,
8EJK
,
8WW2
,
7E9G
,
6XBM
,
7F9Z
,
8GGB
,
8JGB
,
8UNT
,
7XOW
,
7JOZ
,
6XBK
,
8HS3
,
7XV3
,
7D77
,
7U2K
,
8GEF
,
8H4I
,
6X19
,
8H2G
,
7K7Z
,
8JXX
,
7EJA
,
8KFX
,
8IYS
,
8UNX
,
8WCB
,
8JIM
,
7Y64
,
7EZM
,
6XOX
,
8GE1
,
7VL9
,
8UO1
,
7X2C
,
7EW7
,
7QVM
,
8GE8
,
7XBX
,
8ID9
,
8T3Q
,
6EG8
,
8J21
,
7XW5
,
7X2F
,
8UQO
,
6OSA
,
7RKY
,
8HSC
,
8GGC
,
8XZJ
,
8HJ1
,
7D7M
,
7BB6
,
6B3J
,
8WC7
,
8WC3
,
5HE0
,
7UM6
,
7KI1
,
8IRU
,
7VKT
,
8IEC
,
6LFO
,
8SZH
,
8GE2
,
7Y65
,
8XZF
,
8XJN
,
7RKM
,
5HE1
,
8G94
,
7JVP
,
7EW3
,
8JGF
,
7S8N
,
7L0P
,
7TYL
,
6NIY
,
7XP4
,
6LML
,
8JKB
,
8JLR
,
7WKD
,
8GCM
,
7EW1
,
7V6A
,
8HBD
,
6M8S
,
6PT0
,
7EUO
,
8HJ2
,
7F6H
,
6VMS
,
8IJ3
,
8DPH
,
8DZQ
,
5UKM
,
7UM7
,
9AYF
,
7TYX
,
8IRV
,
7EVZ
,
8VY7
,
7RMG
,
8W8R
,
7XA3
,
8GG5
,
7E32
,
8K4N
,
8I97
,
8IYW
,
8U8F
,
7YK6
,
8GFY
,
7DB6
,
8XOJ
,
8KH5
,
6OIK
,
8GCP
,
8J22
,
8W89
,
7L0Q
,
7F6I
,
7E2Y
,
8HNM
,
7VIG
,
8JLJ
,
8DPI
,
8U81
,
8HOC
,
8JT6
,
8FMZ
,
8I9A
,
8H4K
,
7MTS
,
7XTA
,
6PB1
,
8DZR
,
8UNQ
,
7XY7
,
8GUQ
,
8IED
,
8GG6
,
8IZ4
,
8KFY
,
6WHA
,
7XZ5
,
7W7E
,
7VUH
,
8ITF
,
8UNM
,
8GFZ
,
7VIE
,
8GEG
,
7CKW
,
7RAN
,
7S8O
,
8JGG
,
7TYN
,
7JVQ
,
8UNU
,
8E3Y
,
8J23
,
8JZ7
,
8IJA
,
7XMS
,
7VUJ
,
6KPG
,
8U4O
,
7T94
,
7YS6
,
6WI9
,
7WF7
,
8GE9
,
7CMV
,
7WYB
,
8H4L
,
7UTZ
,
7YFD
,
8IZB
,
7X9Y
,
7WVX
,
8IU2
,
7TYY
,
7XTB
,
7T9I
,
9ASB
,
7YP7
,
8FN0
,
7VUZ
,
8IA2
,
8F0J
,
8UNY
,
8K8J
,
6E3Y
,
7XJK
,
7F4F
,
8J6D
,
7Y24
,
8UO2
,
7WY5
,
8JXT
,
7VV5
,
8GEH
,
7X9A
,
8EMX
,
7TUZ
,
8E3Z
,
8T3S
,
7WVV
,
8IJB
,
7XMT
,
7L1U
,
8GGE
,
7CKZ
,
7SF7
,
6CRK
,
8JLK
,
7W40
,
8GEA
,
8HMP
,
7VDL
,
7T8X
,
8WC8
,
7W57
,
7CKX
,
6DDE
,
7F4I
,
7WV9
,
7WVY
,
7TRS
,
7WXW
,
8GUR
,
8XZG
,
8XJO
,
8SZI
,
7WZ4
,
7XKD
,
8WC4
,
8I9L
,
8GE3
,
7W2Z
,
7S1M
,
8IA7
,
8DWC
,
6UUS
,
8FLQ
,
7Y26
,
8JHB
,
7WCM
,
8HVI
,
7WU2
,
8HTI
,
8IUK
,
8HCQ
,
7LD4
,
7CX3
,
7NA7
,
7WUJ
,
8TB0
,
7WU4
,
7F1R
,
7F55
,
7EO4
,
8FU6
,
8J24
,
7W55
,
8HJ5
,
8GEB
,
8VY9
,
8I9S
,
8GD9
,
8HCX
,
7XW6
,
7U2L
,
7F1Z
,
8J6I
,
8H8J
,
6P9Y
,
7WU9
,
8GUS
,
7YDJ
,
7SRR
,
6LI3
,
8GGF
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
10
UniProt:P63211 GNGT1
3
S-farn-GNGT1 [photoreceptor disc membrane]
(R-HSA-2530520)
GNGT1 [photoreceptor disc membrane]
(R-HSA-55393)
GNGT1 [plasma membrane]
(R-HSA-167428)
0.621
3
UniProt:P07237 P4HB
3
P4HB [endoplasmic reticulum lumen]
(R-HSA-174692)
p-P4HB [endoplasmic reticulum lumen]
(R-HSA-8956902)
HC53,56-P4HB [endoplasmic reticulum lumen]
(R-HSA-3341287)
0.556
3
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
4
UniProt:Q13371 PDCL
2
p-S18,S19,S20,S25-PDCL [cytosol]
(R-HSA-6814228)
PDCL [cytosol]
(R-HSA-6813727)
0.527
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.527
10
UniProt:P10824 Gnai1
1
Guanine nucleotide-binding protein G(i), alpha-1 subunit [plasma membrane]
(R-RNO-421889)
0.488
2
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