Reactome | SSU72 [nucleoplasm]

SSU72 [nucleoplasm]

Stable Identifier

R-HSA-6814915

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RNA polymerase II subunit A C-terminal domain phosphatase SSU72, SSU72_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NP77 SSU72

Gene Names

SSU72, HSPC182, PNAS-120

Chain

chain:1-194

Reference Genes

BioGPS Gene:29101 SSU72

COSMIC (genes):SSU72 SSU72

CTD Gene:29101 SSU72

dbSNP Gene:29101 SSU72

ENSEMBL:ENSG00000160075 SSU72

HGNC:25016 SSU72

KEGG:hsa:29101 SSU72

Monarch:29101 SSU72

NCBI Gene:29101 SSU72

OMIM:617680 SSU72

UCSC:Q9NP77 SSU72

Reference Transcript

RefSeq:NM_014188.3 SSU72

This entity regulates

Positively

Integrator complex processes the 3' end of snRNA (Homo sapiens)

Inferred To

SSU72 [nucleoplasm] (Bos taurus)

SSU72 [nucleoplasm] (Canis familiaris)

SSU72 [nucleoplasm] (Gallus gallus)

SSU72 [nucleoplasm] (Sus scrofa)

Ssu72 [nucleoplasm] (Drosophila melanogaster)

Ssu72 [nucleoplasm] (Mus musculus)

Ssu72 [nucleoplasm] (Rattus norvegicus)

ssup-72 [nucleoplasm] (Caenorhabditis elegans)

ssu72 [nucleoplasm] (Danio rerio)

ssu72 [nucleoplasm] (Dictyostelium discoideum)

ssu72 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_054907.1

ENSEMBL

ENSP00000291386, ENST00000291386, ENSG00000160075, ENSP00000351955, ENST00000359060

OpenTargets

ENSG00000160075

ZINC - Substances

SSU72_HUMAN

ZINC target

Q9NP77

PRO

Q9NP77

GlyGen

Q9NP77

PDB

4H3H, 3O2S, 4H3K, 3O2Q

IntEnz

3.1.3.16

GeneCards

SSU72

HPA

ENSG00000160075-SSU72

Pharos - Targets

Q9NP77

ZINC - Predictions - Purchasable

SSU72_HUMAN

HMDB Protein

HMDBP11964

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60216 RAD21	14	RAD21 [nucleoplasm] (R-HSA-163042) RAD21 [chromosome, centromeric region] (R-HSA-2466012) RAD21 [chromosome] (R-HSA-1638775) p-S454-RAD21 [chromosome] (R-HSA-2485164) p-S454-RAD21 [cytosol] (R-HSA-2500310) p-S454-RAD21 [chromosome, centromeric region] (R-HSA-2485163) RAD21(1-172) [chromosome, centromeric region] (R-HSA-2467793) p-S454-RAD21(451-631) [chromosome, centromeric region] (R-HSA-2467790) RAD21(173-450) [chromosome, centromeric region] (R-HSA-2500296) RAD21(1-172) [cytosol] (R-HSA-2484901) RAD21(173-450) [cytosol] (R-HSA-2500308) p-S454-RAD21(451-631) [cytosol] (R-HSA-2500309) RAD21 [cytosol] (R-HSA-2484795) monoSUMO1-K-RAD21 [nucleoplasm] (R-HSA-3108183)	0.674	9
UniProt:Q8N3U4 STAG2	8	STAG2 [nucleoplasm] (R-HSA-163046) STAG2 [chromosome, centromeric region] (R-HSA-2466018) STAG2 [chromosome] (R-HSA-1638777) p-STAG2 [chromosome] (R-HSA-1638793) p-STAG2 [cytosol] (R-HSA-2484806) p-STAG2 [chromosome, centromeric region] (R-HSA-2466013) STAG2 [cytosol] (R-HSA-2484897) monoSUMO1-K-STAG2 [nucleoplasm] (R-HSA-3108187)	0.577	4
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3

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