Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Cyclin E [nucleoplasm]
Stable Identifier
R-HSA-68373
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
Cyclin E associated events during G1/S transition (Homo sapiens)
Association of Rb with Cyclin E:Cdk2 complexes (Homo sapiens)
CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CAK-mediated phosphorylation of Cyclin E:Cdk2 (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Homo sapiens)
Cyclin E:p-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Homo sapiens)
Cyclin E:p-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes (Homo sapiens)
Cyclin E:CDK2-mediated phosphorylation of RB1 (Homo sapiens)
CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Homo sapiens)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Homo sapiens)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cdc6 protein is phosphorylated by CDK (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cdc6 protein is phosphorylated by CDK (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of mitotic cell cycle (Homo sapiens)
Aberrant regulation of mitotic cell cycle due to RB1 defects (Homo sapiens)
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects (Homo sapiens)
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) (Homo sapiens)
Defective RB1 does not bind E2F1,(E2F2,E2F3) (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
Participants
members
CCNE1 [nucleoplasm]
(Homo sapiens)
CCNE2 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
Cyclin E:p-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Inferred To
CycE [nucleoplasm]
(Drosophila melanogaster)
cye-1 [nucleoplasm]
(Caenorhabditis elegans)
Cyclin E [nucleoplasm]
(Bos taurus)
Cyclin E [nucleoplasm]
(Canis familiaris)
Cyclin E [nucleoplasm]
(Danio rerio)
Cyclin E [nucleoplasm]
(Gallus gallus)
Cyclin E [nucleoplasm]
(Mus musculus)
Cyclin E [nucleoplasm]
(Rattus norvegicus)
Cyclin E [nucleoplasm]
(Sus scrofa)
Cyclin E [nucleoplasm]
(Xenopus tropicalis)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
