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RFC3 [nucleoplasm]
Stable Identifier
R-HSA-68431
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RFC38, Activator 1 38 kDa subunit, Replication factor C 38 kDa subunit, A1 38 kDa subunit, RF-C 38 kDa subunit, Replication factor C subunit 3
Locations in the PathwayBrowser for interactor UniProt:O75943 RAD17
Expand all
Cell Cycle (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
Formation of the CTF18-RFC(7s) complex (Homo sapiens)
RFC3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P40938 RFC3
Gene Names
RFC3
Chain
chain:1-356
Reference Genes
BioGPS Gene:5983 RFC3
COSMIC (genes):RFC3 RFC3
CTD Gene:5983 RFC3
dbSNP Gene:5983 RFC3
ENSEMBL:ENSG00000133119 RFC3
HGNC:9971 RFC3
KEGG:hsa:5983 RFC3
Monarch:5983 RFC3
NCBI Gene:5983 RFC3
OMIM:600405 RFC3
UCSC:P40938 RFC3
Reference Transcript
RefSeq:NM_002915.3 RFC3
RefSeq:NM_181558.2 RFC3
Other Identifiers
11718403_at
11718404_at
11754883_a_at
16773946
204127_PM_at
204127_at
204128_PM_s_at
204128_s_at
231119_PM_at
231119_at
3485075
3485076
3485077
3485078
3485079
3485080
3485081
3485082
3485083
3485084
3485088
3485090
3485091
3485114
39269_at
58785_at
5983
78367_at
7968563
A_14_P116670
A_23_P14193
A_32_P197016
A_33_P3214446
GE57577
GO:0000731
GO:0003677
GO:0003689
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005663
GO:0006260
GO:0006261
GO:0006271
GO:0006281
GO:0008094
GO:0016787
GO:0016887
GO:0017116
GO:0031390
GO:0032508
GO:0043226
GO:0046683
GO:0140097
GO:0140657
GO:1900264
HMNXSV003030826
Hs.111458.0.A1_3p_at
ILMN_1658143
ILMN_1711381
ILMN_1784860
L07541_at
PH_hs_0006329
TC13000119.hg
g12803002_3p_at
g4506488_3p_a_at
Participates
as an input of
Formation of the CTF18-RFC(7s) complex (Homo sapiens)
as a component of
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
Inferred To
RFC3 [nucleoplasm]
(Bos taurus)
RFC3 [nucleoplasm]
(Canis familiaris)
RFC3 [nucleoplasm]
(Gallus gallus)
RFC3 [nucleoplasm]
(Plasmodium falciparum)
RFC3 [nucleoplasm]
(Saccharomyces cerevisiae)
RFC3 [nucleoplasm]
(Sus scrofa)
rfc-3 [nucleoplasm]
(Caenorhabditis elegans)
rfc5 [nucleoplasm]
(Schizosaccharomyces pombe)
Rfc3 [nucleoplasm]
(Mus musculus)
Rfc3 [nucleoplasm]
(Rattus norvegicus)
RfC38 [nucleoplasm]
(Drosophila melanogaster)
rfc3 [nucleoplasm]
(Danio rerio)
rfc3 [nucleoplasm]
(Dictyostelium discoideum)
rfc3 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_853536.2
,
NP_002906.1
OpenTargets
ENSG00000133119
ENSEMBL
ENSP00000401001
,
ENST00000380071
,
ENSG00000133119
,
ENST00000434425
,
ENSP00000369411
HPA
ENSG00000133119-RFC3
GeneCards
RFC3
PRO
P40938
Pharos - Targets
P40938
GlyGen
P40938
PDB
8UMV
,
8UMY
,
8UMT
,
8UI9
,
8UI7
,
8UMU
,
8UI8
,
8UMW
,
8UN0
,
7Z6H
,
8UII
,
6VVO
,
8UNJ
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35249 RFC4
1
RFC4 [nucleoplasm]
(R-HSA-68429)
0.821
14
UniProt:O75943 RAD17
1
RAD17 [nucleoplasm]
(R-HSA-3008665)
0.643
3
UniProt:Q5VWX1 KHDRBS2
2
KHDRBS2 [nucleoplasm]
(R-HSA-8849028)
p-Y-KHDRBS2 [nucleoplasm]
(R-HSA-8849031)
0.556
3
UniProt:O75525 KHDRBS3
2
KHDRSB3 [nucleoplasm]
(R-HSA-8849040)
p-Y-KHDRSB3 [nucleoplasm]
(R-HSA-8849035)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:Q6AI12 ANR40
0.556
3
UniProt:Q0VD86 INCA1
0.556
3
UniProt:Q9BVC3 DSCC1
1
DSCC1 [nucleoplasm]
(R-HSA-9668907)
0.527
3
UniProt:P40937 RFC5
1
RFC5 [nucleoplasm]
(R-HSA-68427)
0.527
3
UniProt:P35251 RFC1
1
RFC1 [nucleoplasm]
(R-HSA-68435)
0.499
3
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