Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PCNA [nucleoplasm]
Stable Identifier
R-HSA-68439
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Proliferating cell nuclear antigen, Cyclin
Icon
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G0 and Early G1 (Homo sapiens)
Transcription of E2F targets under negative control by DREAM complex (Homo sapiens)
PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
G1/S-Specific Transcription (Homo sapiens)
PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Formation of Okazaki fragments (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of remaining Flap (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Disassociation of Processive Complex and Completed Telomere End (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
Formation of Processive Complex on the C-strand of the telomere (Homo sapiens)
Processive complex loaded on telomere [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive synthesis on the C-strand of the telomere (Homo sapiens)
Formation of C-strand Okazaki fragments (Homo sapiens)
Processive complex loaded on telomere [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate on the C-strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Joining of adjacent Okazaki fragments of the C-strand (Homo sapiens)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate from the C-strand (Homo sapiens)
RPA binds to the Flap on the C-strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Recruitment of DNA2 endonuclease to the C strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of remaining Flap from the C-strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Resolution of Abasic Sites (AP sites) (Homo sapiens)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Homo sapiens)
PCNA-Dependent Long Patch Base Excision Repair (Homo sapiens)
FEN1 bound to PCNA and APEX1 cleaves flap ssDNA (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
LIG1 bound to APEX1 and PCNA ligates SSB (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLD,POLE-mediated DNA strand displacement synthesis (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
DNA Damage Bypass (Homo sapiens)
Recognition of DNA damage by PCNA-containing replication complex (Homo sapiens)
PCNA-containing replication complex binds damaged dsDNA (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP1:WDR48 binds monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
Termination of translesion DNA synthesis (Homo sapiens)
POLD,POLE binds deISGylated PCNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
TRIM25 binds monoUb:164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP43 binds ISG:K164,ISG:K168-PCNA (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP43 deISGylates ISG:K164,ISG:K168-PCNA (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Translesion Synthesis by POLH (Homo sapiens)
Elongation by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Insertion of correct bases opposite the lesion by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLI (Homo sapiens)
POLI incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLZ elongates POLI-incorporated dNMP (Homo sapiens)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLK (Homo sapiens)
POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by REV1 (Homo sapiens)
POLZ extends translesion synthesis (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1 binds AP-dsDNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1 inserts dCMP opposite to AP sites in DNA (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
D-loop extension by DNA polymerases (Homo sapiens)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Mismatch Repair (Homo sapiens)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Homo sapiens)
EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL) (Homo sapiens)
EXO1:MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 or more bases and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
EXO1 interacts with MSH2:MSH3 (MutSbeta) and MLH1:PMS2 (MutLalpha) (Homo sapiens)
EXO1:MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 or more bases and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 or more bases and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more (Homo sapiens)
MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 bases or more [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 or more bases and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MSH2:MSH3 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Homo sapiens)
MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 bases or more [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Homo sapiens)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Homo sapiens)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Homo sapiens)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Homo sapiens)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Homo sapiens)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Nucleotide Excision Repair (Homo sapiens)
Global Genome Nucleotide Excision Repair (GG-NER) (Homo sapiens)
Dual Incision in GG-NER (Homo sapiens)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in GG-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Homo sapiens)
Dual incision in TC-NER (Homo sapiens)
3' incision by ERCC5 (XPG) in TC-NER (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Homo sapiens)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Formation of Okazaki fragments (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Removal of remaining Flap (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Homo sapiens)
GADD45A binds PCNA (Homo sapiens)
GADD45A:PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
HLTF binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Homo sapiens)
HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
HLTF polyubiquitinates monoubiquitinated PCNA (Homo sapiens)
HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SHPRH polyubiquitinates monoubiquitinated PCNA (Homo sapiens)
SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of DNA replication proteins (Homo sapiens)
SUMOylation of PCNA with SUMO1 (Homo sapiens)
PCNA [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12004 PCNA
Gene Names
PCNA
Chain
chain:1-261
Reference Genes
BioGPS Gene:5111 PCNA
COSMIC (genes):PCNA PCNA
CTD Gene:5111 PCNA
dbSNP Gene:5111 PCNA
ENSEMBL:ENSG00000132646 PCNA
ENSEMBL:ENSG00000132646.11 PCNA
HGNC:8729 PCNA
KEGG Gene (Homo sapiens):5111 PCNA
Monarch:5111 PCNA
NCBI Gene:5111 PCNA
OMIM:176740 PCNA
UCSC:P12004 PCNA
Reference Transcript
RefSeq:NM_182649.1 PCNA
RefSeq:NM_002592.2 PCNA
Other Identifiers
11716103_a_at
16916958
1824_s_at
1884_s_at
201202_PM_at
201202_at
3896201
3896202
3896203
3896204
3896206
3896207
3896209
3896211
3896213
3896214
3896215
3896216
4006657
4006658
5111
8064844
A_23_P28886
A_33_P3258612
GE61312
GO:0000122
GO:0000228
GO:0000278
GO:0000307
GO:0000701
GO:0000781
GO:0000785
GO:0001673
GO:0003677
GO:0003682
GO:0003684
GO:0003824
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005652
GO:0005654
GO:0005657
GO:0005694
GO:0005813
GO:0005815
GO:0005856
GO:0006260
GO:0006272
GO:0006275
GO:0006281
GO:0006287
GO:0006298
GO:0006351
GO:0006355
GO:0006974
GO:0006979
GO:0007507
GO:0016604
GO:0016787
GO:0019899
GO:0019985
GO:0022414
GO:0030154
GO:0030331
GO:0030337
GO:0030855
GO:0030894
GO:0030971
GO:0031297
GO:0032077
GO:0032139
GO:0032200
GO:0032355
GO:0032405
GO:0033993
GO:0034644
GO:0035035
GO:0042802
GO:0043226
GO:0043596
GO:0043626
GO:0044849
GO:0044877
GO:0045739
GO:0045740
GO:0046686
GO:0048856
GO:0070062
GO:0070182
GO:0070301
GO:0070557
GO:0071466
GO:0071548
GO:0097421
GO:0098772
GO:0140097
GO:1900264
GO:1902065
GO:1902990
HMNXSV003000505
HMNXSV003026895
ILMN_1685682
ILMN_1694177
ILMN_1706958
J05614_at
M15796_at
PH_hs_0028994
TC20000592.hg
g4505640_3p_at
Participates
as an input of
SUMOylation of PCNA with SUMO1 (Homo sapiens)
as a component of
ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
PCNA homotrimer [nucleoplasm] (Homo sapiens)
as an output of
PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex (Homo sapiens)
Other forms of this molecule
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
K63polyUb-K164-PCNA [nucleoplasm]
ISG-K164,ISG-K168-PCNA [nucleoplasm]
MonoUb-K164-PCNA [nucleoplasm]
Inferred To
PCNA [nucleoplasm]
(Bos taurus)
PCNA [nucleoplasm]
(Canis familiaris)
PCNA [nucleoplasm]
(Drosophila melanogaster)
PCNA [nucleoplasm]
(Gallus gallus)
PCNA [nucleoplasm]
(Sus scrofa)
PCNA1 [nucleoplasm]
(Plasmodium falciparum)
pcna [nucleoplasm]
(Danio rerio)
pcna [nucleoplasm]
(Dictyostelium discoideum)
Pcna [nucleoplasm]
(Mus musculus)
Pcna [nucleoplasm]
(Rattus norvegicus)
clip1 [nucleoplasm]
(Xenopus tropicalis)
POL30 [nucleoplasm]
(Saccharomyces cerevisiae)
pcn-1 [nucleoplasm]
(Caenorhabditis elegans)
pcn1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_872590.1
,
NP_002583.1
ZINC - World Drugs
PCNA_HUMAN
OpenTargets
ENSG00000132646
ZINC - FDA approved
PCNA_HUMAN
ZINC - Substances
PCNA_HUMAN
ZINC - Biogenic
PCNA_HUMAN
ZINC target
P12004
PRO
P12004
PDB
7NV0
,
6FCM
,
3JA9
,
5MOM
,
7EFA
,
2ZVL
,
7QO1
,
3WGW
,
5YD8
,
3P87
,
6TNY
,
5E0U
,
1U7B
,
5E0V
,
6TNZ
,
5MLO
,
4RJF
,
6K3A
,
1AXC
,
6EHT
,
4ZTD
,
6CBI
,
6S1N
,
7M5M
,
6S1O
,
6FCN
,
6GIS
,
5MAV
,
6QC0
,
7M5L
,
7QNZ
,
2ZVK
,
6GWS
,
3TBL
,
7NV1
,
2ZVM
,
1VYM
,
3VKX
,
1U76
,
8B8T
,
6QCG
,
5MLW
,
1UL1
,
5YCO
,
1W60
,
6HVO
,
6VVO
,
4D2G
,
1VYJ
,
7M5N
,
5E0T
,
6S1M
,
7KQ0
,
5IY4
,
7KQ1
ZINC - Metabolites
PCNA_HUMAN
HPA
ENSG00000132646-PCNA
GeneCards
P12004
Ensembl
ENST00000379143
,
ENST00000379160
,
ENSG00000132646
,
ENSP00000368458
,
ENSP00000368438
Pharos - Targets
P12004
ZINC - Predictions - Purchasable
PCNA_HUMAN
Orphanet
23426
Interactors (47)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38936 CDKN1A
5
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
CDKN1A [cytosol]
(R-HSA-182512)
CDKN1A [nucleoplasm]
(R-HSA-182585)
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
0.976
37
UniProt:P39748 FEN1
1
FEN1 [nucleoplasm]
(R-HSA-54745)
0.956
19
UniProt:P12004 PCNA
5
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
(R-HSA-4615861)
K63polyUb-K164-PCNA [nucleoplasm]
(R-HSA-8943000)
ISG-K164,ISG-K168-PCNA [nucleoplasm]
(R-HSA-5653768)
MonoUb-K164-PCNA [nucleoplasm]
(R-HSA-5651986)
PCNA [nucleoplasm]
(R-HSA-68439)
0.898
11
UniProt:Q15054 POLD3
1
POLD3 [nucleoplasm]
(R-HSA-68445)
0.83
7
IntAct:EBI-4399559 UBIQ
0.811
7
UniProt:Q15004 PCLAF
2
KIAA0101 [nucleoplasm]
(R-HSA-5655178)
MonoUb-K15,K24-KIAA0101 [nucleoplasm]
(R-HSA-5655182)
0.742
5
UniProt:Q13111 CAF1A
0.734
4
UniProt:P20585 MSH3
2
MSH3 K383Rfs*32 [nucleoplasm]
(R-HSA-5578664)
MSH3 [nucleoplasm]
(R-HSA-5357519)
0.718
6
UniProt:P49005 POLD2
1
POLD2 [nucleoplasm]
(R-HSA-68443)
0.678
3
UniProt:O95944 NCR2
1
NCR2 [plasma membrane]
(R-HSA-197652)
0.672
7
UniProt:P28340 POLD1
2
POLD1 [nucleoplasm]
(R-HSA-68449)
POLD1 [cytosol]
(R-HSA-2564763)
0.669
3
UniProt:A2RU14 TM218
0.666
4
UniProt:Q9Z111 GA45G
0.664
9
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
14
UniProt:P42771 CDKN2A
20
p16INK4A D84G [cytosol]
(R-HSA-9632461)
p16INK4A E88* [cytosol]
(R-HSA-9632588)
p16INK4A R87P [cytosol]
(R-HSA-9632335)
p16INK4A V126D [cytosol]
(R-HSA-9631055)
p16INK4A W110* [cytosol]
(R-HSA-9632585)
p16INK4A D84H [cytosol]
(R-HSA-9632489)
p16INK4A R80* [cytosol]
(R-HSA-9632586)
p16INK4A P114L [cytosol]
(R-HSA-9630916)
p16INK4A R58* [cytosol]
(R-HSA-9632582)
p16INK4A D84N [cytosol]
(R-HSA-9632483)
p16INK4A M53I [cytosol]
(R-HSA-9630911)
p16INK4A D84Y [cytosol]
(R-HSA-9632478)
p16INK4A G101W [cytosol]
(R-HSA-9631257)
p16INK4A P81L [cytosol]
(R-HSA-9632280)
p16INK4A A20P [cytosol]
(R-HSA-9630805)
p16INK4A D84V [cytosol]
(R-HSA-9632465)
p16INK4A P81T [cytosol]
(R-HSA-9632275)
p16INK4A P81H [cytosol]
(R-HSA-9632293)
p16INK4A D84A [cytosol]
(R-HSA-9632486)
p16INK4A P81R [cytosol]
(R-HSA-9632294)
0.61
8
UniProt:Q5FWF4 ZRAB3
0.599
8
UniProt:Q9H063 MAF1
3
p-S60,S68,S75-MAF1 [cytosol]
(R-HSA-8944455)
MAF1 [cytosol]
(R-HSA-8944460)
MAF1 [nucleoplasm]
(R-HSA-8944422)
0.581
4
UniProt:P30041 PRDX6
3
PRDX6 [extracellular region]
(R-HSA-6806198)
PRDX6 [azurophil granule lumen]
(R-HSA-6798744)
PRDX6 [cytosol]
(R-HSA-3343670)
0.573
2
UniProt:P61769 B2M
11
B2M(21-119) [early endosome membrane]
(R-HSA-182298)
B2M(21-119) [early endosome lumen]
(R-HSA-1236827)
B2M(21-119) [phagocytic vesicle membrane]
(R-HSA-1236891)
B2M(21-119) [recycling endosome membrane]
(R-HSA-8863880)
B2M(21-119) [Golgi membrane]
(R-HSA-983403)
B2M(21-119) [ER to Golgi transport vesicle membrane]
(R-HSA-983378)
B2M(21-119) [tertiary granule lumen]
(R-HSA-6800179)
B2M(21-119) [extracellular region]
(R-HSA-1302721)
B2M(21-119) [specific granule lumen]
(R-HSA-6806144)
B2M(21-119) [endoplasmic reticulum lumen]
(R-HSA-983063)
B2M(21-119) [plasma membrane]
(R-HSA-167743)
0.573
3
UniProt:P68104 EEF1A1
7
Me3K79-EEF1A1 [cytosol]
(R-HSA-8932212)
Me3K318-EEF1A1 [cytosol]
(R-HSA-8932419)
EEF1A1 [secretory granule lumen]
(R-HSA-6801479)
EEF1A1 [extracellular region]
(R-HSA-6806456)
EEF1A1 [ficolin-1-rich granule lumen]
(R-HSA-6801528)
EEF1A1 [cytosol]
(R-HSA-156905)
EEF1A1 [lysosomal membrane]
(R-HSA-9626022)
0.573
2
UniProt:P00558 PGK1
1
PGK1 [cytosol]
(R-HSA-70483)
0.573
2
UniProt:P07355 ANXA2
4
ANXA2 [cytosol]
(R-HSA-5263667)
ANXA2 [external side of plasma membrane]
(R-HSA-5336164)
ANXA2 [extracellular region]
(R-HSA-6806242)
ANXA2 [azurophil granule lumen]
(R-HSA-6798766)
0.573
2
UniProt:P04075 ALDOA
6
ALDOA [platelet alpha granule lumen]
(R-HSA-349738)
ALDOA [tertiary granule lumen]
(R-HSA-6801485)
ALDOA [secretory granule lumen]
(R-HSA-6801469)
ALDOA [extracellular region]
(R-HSA-349735)
ALDOA [ficolin-1-rich granule lumen]
(R-HSA-6801521)
ALDOA [cytosol]
(R-HSA-71492)
0.571
3
UniProt:P04406 GAPDH
1
GAPDH [cytosol]
(R-HSA-70428)
0.571
3
UniProt:P06733 ENO1
1
ENO1 [cytosol]
(R-HSA-71437)
0.571
3
UniProt:Q14527 HLTF
1
HLTF [nucleoplasm]
(R-HSA-8855007)
0.564
2
UniProt:P61970 NTF2
0.556
3
UniProt:Q9NZD8 SPG21
0.556
3
UniProt:Q96DZ9-2 CMTM5
0.556
3
UniProt:Q8IWU4 SLC30A8
2
SLC30A8 [Golgi membrane]
(R-HSA-9817561)
SLC30A8 [secretory granule membrane]
(R-HSA-437106)
0.556
3
UniProt:P03129 VE7
0.547
2
UniProt:A8CG34 POM121C
1
POM121C [nuclear envelope]
(R-HSA-6805165)
0.547
2
UniProt:Q8IWL3 HSCB
5
HSCB [mitochondrial matrix]
(R-HSA-1299438)
HSCB [mitochondrial inner membrane]
(R-HSA-1299447)
HSCB(1-235) [mitochondrial inner membrane]
(R-HSA-1299443)
HSCB(1-30) [mitochondrial matrix]
(R-HSA-8986120)
HSCB(1-235) [mitochondrial intermembrane space]
(R-HSA-1299456)
0.547
2
UniProt:P18669 PGAM1
4
PGAM1 [secretory granule lumen]
(R-HSA-6803293)
PGAM1 [extracellular region]
(R-HSA-6806482)
PGAM1 [ficolin-1-rich granule lumen]
(R-HSA-6803309)
PGAM1 [cytosol]
(R-HSA-71442)
0.544
2
UniProt:P60174 TPI1
1
TPI1 [cytosol]
(R-HSA-70451)
0.544
2
UniProt:Q9H160 ING2
2
monoSUMO1-K195-ING2 [nucleoplasm]
(R-HSA-4086075)
ING2 [nucleoplasm]
(R-HSA-3215167)
0.544
3
UniProt:P03950 ANG
2
ANG [cytosol]
(R-HSA-9708345)
ANG [extracellular region]
(R-HSA-5692435)
0.537
4
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P24941 CDK2
5
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
CDK2 [cytosol]
(R-HSA-157440)
CDK2 [nucleoplasm]
(R-HSA-68365)
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
0.527
2
UniProt:Q9HCU8 POLD4
1
POLD4 [nucleoplasm]
(R-HSA-68447)
0.524
4
UniProt:Q86TU7 SETD3
1
SETD3 [nucleoplasm]
(R-HSA-5688411)
0.508
3
UniProt:Q1K9H5 Q1K9H5
0.508
2
UniProt:B4URF7 B4URF7
0.508
2
UniProt:Q9UBF6 RNF7
1
RNF7 (RBX2) [cytosol]
(R-HSA-8863132)
0.508
3
UniProt:Q8TE30 Q8TE30
0.499
6
UniProt:Q9H211 CDT1
1
CDT1 [nucleoplasm]
(R-HSA-68536)
0.499
2
UniProt:P57081 WDR4
1
WDR4 [nucleoplasm]
(R-HSA-6782341)
0.462
3
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
![PCNA [nucleoplasm] icon](/icon/R-ICO-013160.svg){kind=icon}
