Reactome | Orc1 removal from chromatin

Orc1 removal from chromatin

Stable Identifier

R-HSA-68949

Type

Pathway

Species

Homo sapiens

Compartment

nucleoplasm, cytosol

ReviewStatus

5/5

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Mammalian Orc1 protein is phosphorylated and selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle.

Literature References

PubMed ID	Title	Journal	Year
11931757	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. Hidaka, M, Tansey, WP, Zou-Yang, XH, Mendez, J, Stillman, B, Kim, SY	Mol Cell	2002
11809796	Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replication. Knippers, R, Keller, C, Ladenburger, EM	Mol Cell Biol	2002
1110244	Forearm blood flow during body temperature transients produced by leg exercise. Nadel, ER, Roberts, MF, Stolwijk, JA, Wenger, CB	J Appl Physiol	1975
11739726	Mammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle. DePamphilis, ML, Li, CJ	Mol Cell Biol	2001