Reactome | Orc1 removal from chromatin

Orc1 removal from chromatin

Stable Identifier

R-HSA-68949

Type

Pathway

Species

Homo sapiens

Compartment

nucleoplasm, cytosol

ReviewStatus

5/5

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Mammalian Orc1 protein is phosphorylated and selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle.

Literature References

PubMed ID	Title	Journal	Year
11931757	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. Mendez, J, Zou-Yang, XH, Kim, SY, Hidaka, M, Tansey, WP, Stillman, B	Mol Cell	2002
11809796	Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replication. Ladenburger, EM, Keller, C, Knippers, R	Mol Cell Biol	2002
1110244	Forearm blood flow during body temperature transients produced by leg exercise. Wenger, CB, Roberts, MF, Stolwijk, JA, Nadel, ER	J Appl Physiol	1975
11739726	Mammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle. Li, CJ, DePamphilis, ML	Mol Cell Biol	2001