Formation of Cyclin E:Cdk2 complexes

Stable Identifier
R-HSA-69191
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Formation of Cyclin E:Cdk2 complexes
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The E-type cyclins and Cyclin Dependent Kinase 2 control the transition from G1 to S phase. Cdk2 is competent to carry out the necessary reactions only when complexed with Cyclin E.

Literature References
PubMed ID Title Journal Year
7799941 Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2.

Wessling, HC, Desai, D, Fisher, RP, Morgan, DO

Mol Cell Biol 1995
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Orthologous Events
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Formation of Cyclin E:Cdk2 complexes (Drosophila melanogaster)
Formation of Cyclin E:Cdk2 complexes (Gallus gallus)
Formation of Cyclin E:Cdk2 complexes (Mus musculus)
Formation of Cyclin E:Cdk2 complexes (Rattus norvegicus)
Formation of Cyclin E:Cdk2 complexes (Saccharomyces cerevisiae)
Formation of Cyclin E:Cdk2 complexes (Schizosaccharomyces pombe)
Formation of Cyclin E:Cdk2 complexes (Sus scrofa)
Formation of Cyclin E:Cdk2 complexes (Xenopus tropicalis)
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