Ubiquitination of phosphorylated Cdc25A

Stable Identifier
R-HSA-69598
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ubiquitination of phosphorylated Cdc25A
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At the beginning of this reaction, 1 molecule of 'ubiquitin', and 1 molecule of 'phospho-Cdc25A' are present. At the end of this reaction, 1 molecule of 'Ubiquitinated Phospho-Cdc25A' is present.

This reaction takes place in the 'cytosol' and is mediated by the 'ubiquitin-protein ligase activity' of 'Ubiquitin ligase' (Bernardi et al. 2000).

Literature References
PubMed ID Title Journal Year
10828887 Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation

Bernardi, R, Hoffman, B, Liebermann, DA

Oncogene 2000
Participants
Input
Output
Participates
as an event of
Catalyst Activity

ubiquitin-protein transferase activity of Ubiquitin ligase [cytosol]

Physical Entity
Ubiquitin ligase [cytosol] (Homo sapiens)
Activity
ubiquitin-protein transferase activity (GO:0004842)
Created
Hoffmann, I  (2003-06-05)
Cite Us!