Proteolytic degradation of ubiquitinated-Cdc25A

Stable Identifier
R-HSA-69600
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'Ubiquitinated Phospho-Cdc25A' is present. At the end of this reaction, 1 molecule of 'Amino Acid' is present.

This reaction takes place in the 'cytosol' and is mediated by the 'endopeptidase activity' of '26S proteasome' (Bernardi et al. 2000).

Literature References
PubMed ID Title Journal Year
10828887 Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation

Bernardi, R, Liebermann, DA, Hoffman, B

Oncogene 2000
Participants
Participates
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Orthologous Events
Created
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