PXLP-K314-GPT [cytosol]

Stable Identifier
R-HSA-70520
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Alanine aminotransferase , Glutamic--pyruvic transaminase, GPT, glutamic-alanine transaminase, glutamic-pyruvic transaminase
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
1931970 Complete amino acid sequence of human liver cytosolic alanine aminotransferase (GPT) determined by a combination of conventional and mass spectral methods

Oyama, R, Suzuki, M, Takio, K, Ishiguro, M, Titani, K, Matsuzawa, T

Biochemistry 1991
External Reference Information
External Reference
UniProt:P24298 GPT
Gene Names
GPT, AAT1, GPT1
Chain
initiator methionine:, chain:2-496
Reference Genes
BioGPS Gene:2875 GPT
COSMIC (genes):GPT GPT
CTD Gene:2875 GPT
dbSNP Gene:2875 GPT
ENSEMBL:ENSG00000167701 GPT
ENSEMBL_homo_sapiens_GENE:ENSG00000167701.14 GPT
HGNC:4552 GPT
KEGG Gene (Homo sapiens):2875 GPT
Monarch:2875 GPT
NCBI Gene:2875 GPT
OMIM:138200 GPT
UCSC:P24298 GPT
Reference Transcript
Other Identifiers
11745594_x_at
11747456_a_at
11748915_a_at
11752857_x_at
11763604_x_at
17073890
206709_PM_x_at
206709_x_at
2875
3120654
3120657
3120658
3120659
3120660
3120662
3120664
3120666
3120669
3120671
3120674
3120676
3120678
3120680
3120681
34430_at
8148902
A_23_P146339
A_33_P3301871
GE59371
GO:0003824
GO:0004021
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005975
GO:0006520
GO:0008483
GO:0009058
GO:0016740
GO:0030170
GO:0031667
GO:0032869
GO:0042594
GO:0042853
GO:0043226
GO:0045722
GO:0070062
HMNXSV003016560
ILMN_1795257
PH_hs_0029068
TC08000856.hg
U70732_rna1_at
g4885350_3p_at
g4885350_3p_x_at
Participates
as a component of
Inferred To
PPP1R16A [cytosol] (Sus scrofa)
ALT1 [cytosol] (Saccharomyces cerevisiae)
GPT [cytosol] (Bos taurus)
GPT [cytosol] (Canis familiaris)
PXLP-K314-GPT [cytosol] (Caenorhabditis elegans)
PXLP-K314-GPT [cytosol] (Danio rerio)
gpt2 [cytosol] (Xenopus tropicalis)
Gpt [cytosol] (Mus musculus)
Gpt [cytosol] (Rattus norvegicus)
gpt [cytosol] (Dictyostelium discoideum)
ALT [cytosol] (Drosophila melanogaster)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 314
Coordinate
314
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
ZINC target
Ensembl
PRO
Pharos - Targets
HMDB Protein
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