2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]

Stable Identifier
R-HSA-70555
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'NH4+', 1 molecule of 'HCO3-', and 1 molecule of 'ATP' are present. At the end of this reaction, 1 molecule of 'Carbamoyl phosphate', 1 molecule of 'ADP', and 1 molecule of 'Orthophosphate' are present.

This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'carbamoyl-phosphate synthase (ammonia) activity' of 'carbamoyl-phosphate synthetase I dimer'.
Literature References
Participants
Participates
Catalyst Activity

carbamoyl-phosphate synthase (ammonia) activity of CPS1 [mitochondrial matrix]

This event is regulated
Positively by
Orthologous Events
Cross References
Rhea
Authored
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