aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]

Stable Identifier
R-HSA-70599
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytosolic asparagine synthase (ASNS) catalyzes the reaction of aspartate, glutamine, and ATP to form asparagine, glutamate, AMP, and pyrophosphate. Studies of the recombinant protein expressed in E. coli suggest that the active form of the enzyme is a dimer (Van Heeke and Schuster 1989).

Literature References
PubMed ID Title Journal Year
2564390 Expression of human asparagine synthetase in Escherichia coli

Van Heeke, G, Schuster, SM

J Biol Chem 1989
Participants
Participates
Catalyst Activity

asparagine synthase (glutamine-hydrolyzing) activity of ASNS dimer [cytosol]

Orthologous Events
Cross References
Rhea
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