acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]

Stable Identifier
R-HSA-71691
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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ALDH1A1 (aldehyde dehydrogenase) in the cytosol catalyzes the reaction of acetaldehyde and NAD+ to form acetate and NADH + H+ (Inoue et al. 1979). The active form of the enzyme is a tetramer (Ni et al. 1999).
Literature References
PubMed ID Title Journal Year
10631996 Human liver mitochondrial aldehyde dehydrogenase: three-dimensional structure and the restoration of solubility and activity of chimeric forms

Zhou, J, Hurley, TD, Ni, L, Weiner, H

Protein Sci 1999
224930 Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes.

Yamasawa, K, Inoue, K, Nishimukai, H

Biochim Biophys Acta 1979
Participants
Participates
Catalyst Activity

aldehyde dehydrogenase (NAD+) activity of ALDH1A1 tetramer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
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