Reactome | HNRNPH1 [nucleoplasm]

HNRNPH1 [nucleoplasm]

Stable Identifier

R-HSA-71941

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

hnRNP H, ROH1_HUMAN, Heterogeneous nuclear ribonucleoprotein H

Locations in the PathwayBrowser for interactor UniProt:O15160 POLR1C

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External Reference Information

External Reference

UniProt:P31943 HNRNPH1

Gene Names

HNRNPH1, HNRPH, HNRPH1

Chain

initiator methionine:1, chain:1-449, chain:2-449

Reference Genes

BioGPS Gene:3187 HNRNPH1

COSMIC (genes):HNRNPH1 HNRNPH1

CTD Gene:3187 HNRNPH1

dbSNP Gene:3187 HNRNPH1

ENSEMBL:ENSG00000169045 HNRNPH1

ENSEMBL:ENSG00000284254 HNRNPH1

HGNC:5041 HNRNPH1

KEGG Gene (Homo sapiens):3187 HNRNPH1

Monarch:3187 HNRNPH1

NCBI Gene:3187 HNRNPH1

OMIM:601035 HNRNPH1

UCSC:P31943 HNRNPH1

Reference Transcript

Other Identifiers

0005390161

11743099_a_at

17003682

201031_PM_s_at

201031_s_at

213470_3p_s_at

213470_PM_s_at

213470_s_at

2379158

2844185

2857385

2857393

2890150

2890151

2890152

2890154

2890156

2890158

2890159

2890162

2890164

2890165

2890167

2890168

2890170

2890172

2890175

2890178

2890179

2890180

2890181

2890182

2890183

2890184

2890186

3187

3249757

41292_at

79883_at

8116297

A_21_P0004082

A_21_P0004344

A_24_P320254

A_24_P337380

GE885837

GO:0000398

GO:0003674

GO:0003676

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0005737

GO:0005829

GO:0006396

GO:0006397

GO:0008150

GO:0008266

GO:0008380

GO:0016020

GO:0032991

GO:0034641

GO:0042802

GO:0043226

GO:0043484

GO:0071013

GO:1990904

HMNXSV003016247

HMNXSV003039617

HMNXSV003049353

Hs.245710.2.S1_3p_a_at

Hs.245710.2.S2_3p_a_at

ILMN_1702273

ILMN_2101920

ILMN_2101928

ILMN_3246409

L22009_at

PH_hs_0023001

TC05002778.hg

g5031752_3p_at

Participates

as a component of

as an input of

Formation of pre-mRNPs (Homo sapiens)

as an output of

Cleavage at the 3'-Splice Site and Exon Ligation (Homo sapiens)

Inferred To

HNRNPH1 [nucleoplasm] (Bos taurus)

HNRNPH1 [nucleoplasm] (Canis familiaris)

HNRNPH1 [nucleoplasm] (Sus scrofa)

Homologues of HNRNPH1 [nucleoplasm] (Caenorhabditis elegans)

glo [nucleoplasm] (Drosophila melanogaster)

Hnrnph1 [nucleoplasm] (Mus musculus)

Hnrnph1 [nucleoplasm] (Rattus norvegicus)

hrpf-2 [nucleoplasm] (Caenorhabditis elegans)

HNRNPH2 [nucleoplasm] (Gallus gallus)

hnrnph1 [nucleoplasm] (Danio rerio)

hnrnph1 [nucleoplasm] (Xenopus tropicalis)

hrpf-1 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

XP_016864905.1, NP_005511.1, NP_001244222.1, XP_016864906.1, XP_016864904.1

OpenTargets

ENSG00000169045

HPA

ENSG00000169045-HNRNPH1

GeneCards

P31943

Ensembl

ENSG00000284254, ENSG00000169045, ENST00000356731, ENSP00000495786, ENST00000643310, ENSP00000377082, ENST00000638505, ENSP00000349168, ENST00000393432, ENST00000442819, ENSP00000492076, ENSP00000397797

PRO

P31943

Pharos - Targets

P31943

Orphanet

22248

PDB

2LXU, 6DHS

Interactors (43)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13148 TADBP			0.666	7
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.601	4
UniProt:Q9H0Z9 RBM38			0.556	3
UniProt:Q9BXF9 TEKT3			0.556	3
UniProt:P09234 SNRPC	1	SNRPC [nucleoplasm] (R-HSA-8865876)	0.556	3
UniProt:P14678-2 SNRPB			0.556	3
IntAct:EBI-22384931 CCSB ORF ID			0.556	3
UniProt:Q86VE0 MYPOP			0.556	3
UniProt:Q96DH6 MSI2	1	MSI2 [cytosol] (R-HSA-9715155)	0.556	3
UniProt:Q96EL3 MRPL53	1	MRPL53 [mitochondrial inner membrane] (R-HSA-5368226)	0.556	3
UniProt:P31943 HNRNPH1	1	HNRNPH1 [nucleoplasm] (R-HSA-71941)	0.556	3
UniProt:Q7KZS0 Q7KZS0			0.556	3
UniProt:Q9NZD8 SPG21			0.556	3
UniProt:P52597 HNRNPF	2	HNRNPF [plasma membrane] (R-HSA-8950714) HNRNPF [nucleoplasm] (R-HSA-71937)	0.556	3
UniProt:Q9BTL3 RAMAC			0.556	3
UniProt:O75909-2 CCNK			0.556	3
UniProt:Q8NEC5 CATSPER1	1	CATSPER1 [plasma membrane] (R-HSA-2534335)	0.556	3
UniProt:Q9BRJ7 TIRR			0.556	3
UniProt:Q8TAP4-4 LMO3			0.556	3
UniProt:Q96HB5 CC120			0.556	3
UniProt:Q8WW24 TEKT4			0.556	3
UniProt:Q7Z5V6-2 PPP1R32			0.556	3
UniProt:Q8NI38 IKBD			0.556	3
UniProt:Q5VV41 ARHGEF16	1	ARHGEF16 [cytosol] (R-HSA-2976623)	0.556	3
UniProt:Q9H0I2 ENKD1			0.556	3
UniProt:O95872 GPAN1			0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:P50542-3 PEX5			0.556	3
UniProt:Q86Y13 DZIP3	1	DZIP3 [cytosol] (R-HSA-976002)	0.556	3
UniProt:P78317 RNF4	2	RNF4 [nucleoplasm] (R-HSA-5684076) RNF4 [cytosol] (R-HSA-975974)	0.556	3
UniProt:Q9HBE1-4 PATZ1			0.556	6
UniProt:O43251-10 RBFOX2			0.556	3
UniProt:P25800 LMO1	1	LMO1 [nucleoplasm] (R-HSA-8956514)	0.556	3
UniProt:Q52LG2 KRTAP13-2	1	KRTAP13-2 [cytosol] (R-HSA-6810274)	0.556	3
UniProt:P52272 HNRNPM	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.556	3
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.556	3
UniProt:Q92841 DDX17	2	DDX17 [nucleoplasm] (R-HSA-3900090) monoSUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104)	0.556	3
UniProt:Q8TDS5 OXER1	1	OXER1 [plasma membrane] (R-HSA-416425)	0.556	3
UniProt:Q13227 GPS2	1	GPS2 [nucleoplasm] (R-HSA-351642)	0.556	3
UniProt:P09651 HNRNPA1	1	HNRNPA1 [nucleoplasm] (R-HSA-71927)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.527	10
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.527	2
UniProt:Q9NR56 MBNL1			0.499	2

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