Reactome | NUDT21 [nucleoplasm]

NUDT21 [nucleoplasm]

Stable Identifier

R-HSA-72010

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CF I - 25 kDa subunit, Cleavage Factor I 25 kDa subunit, CPSF5

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O43809 NUDT21

Gene Names

NUDT21, CFIM25, CPSF25, CPSF5

Chain

initiator methionine:, chain:2-227

Reference Genes

BioGPS Gene:11051 NUDT21

COSMIC (genes):NUDT21 NUDT21

CTD Gene:11051 NUDT21

dbSNP Gene:11051 NUDT21

ENSEMBL:ENSG00000167005 NUDT21

ENSEMBL_homo_sapiens_GENE:ENSG00000167005.14 NUDT21

HGNC:13870 NUDT21

KEGG Gene (Homo sapiens):11051 NUDT21

Monarch:11051 NUDT21

NCBI Gene:11051 NUDT21

OMIM:604978 NUDT21

UCSC:O43809 NUDT21

Reference Transcript

RefSeq:NM_007006.2 NUDT21

Other Identifiers

11051

11718401_a_at

11718402_a_at

11756899_a_at

16826708

202697_PM_at

202697_at

213461_3p_at

213461_PM_at

213461_at

224830_PM_at

224830_at

3692894

3692896

3692897

3692898

3692899

3692900

3692901

3692903

3692904

3692909

3692913

3692915

3692916

3692917

3692918

39142_at

4048119

64044_at

8001496

90992_at

A_23_P129614

A_24_P287756

A_33_P3418942

GE55148

GE86161

GO:0003682

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005847

GO:0005849

GO:0005856

GO:0006378

GO:0006397

GO:0010608

GO:0016071

GO:0016604

GO:0030154

GO:0031124

GO:0034451

GO:0035925

GO:0042382

GO:0042802

GO:0042803

GO:0042826

GO:0043226

GO:0048856

GO:0051262

GO:0051290

GO:0065003

GO:0110104

GO:1990120

GO:2000738

GO:2000975

HMNXSV003003268

Hs.288061.1.S1_3p_at

Hs.288061.1.S1_3p_s_at

Hs.288061.1.S1_3p_x_at

Hs.301528.1.A1_3p_at

ILMN_1798886

ILMN_2133146

PH_hs_0026091

TC16001133.hg

g5901925_3p_at

Participates

as a component of

CF I [nucleoplasm] (Homo sapiens)

Inferred To

Cpsf5 [nucleoplasm] (Drosophila melanogaster)

cfim-1 [nucleoplasm] (Caenorhabditis elegans)

NUDT21 [nucleoplasm] (Bos taurus)

NUDT21 [nucleoplasm] (Canis familiaris)

NUDT21 [nucleoplasm] (Gallus gallus)

NUDT21 [nucleoplasm] (Sus scrofa)

nudt21 [nucleoplasm] (Danio rerio)

nudt21 [nucleoplasm] (Dictyostelium discoideum)

nudt21 [nucleoplasm] (Xenopus tropicalis)

Nudt21 [nucleoplasm] (Mus musculus)

Nudt21 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_008937.1

OpenTargets

ENSG00000167005

GeneCards

O43809

HPA

ENSG00000167005-NUDT21

Ensembl

ENST00000300291, ENSP00000300291, ENSG00000167005

PRO

O43809

Pharos - Targets

O43809

PDB

3Q2T, 3N9U, 2CL3, 5R4U, 3MDI, 5R64, 3BHO, 5R66, 5R65, 5R4R, 3P5T, 5R4Q, 5R4S, 3BAP, 3MDG, 5R4P, 5R67, 3P6Y, 3Q2S, 5R4T, 2J8Q

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.718	6
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q86X55 CARM1	1	CARM1 [nucleoplasm] (R-HSA-400139)	0.508	2
UniProt:P61978 HNRNPK	2	polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532) HNRNPK [nucleoplasm] (R-HSA-71945)	0.462	2