Reactome | hSLU7 [nucleoplasm]

hSLU7 [nucleoplasm]

Stable Identifier

R-HSA-72073

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pre-mRNA splicing factor SLU7, SLU7_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q96N21 AP4AT

Expand all

External Reference Information

External Reference

UniProt:O95391 SLU7

Gene Names

SLU7

Chain

initiator methionine:, chain:2-586

Reference Genes

BioGPS Gene:10569 SLU7

COSMIC (genes):SLU7 SLU7

CTD Gene:10569 SLU7

dbSNP Gene:10569 SLU7

ENSEMBL:ENSG00000164609 SLU7

ENSEMBL_homo_sapiens_GENE:ENSG00000164609.10 SLU7

HGNC:16939 SLU7

KEGG Gene (Homo sapiens):10569 SLU7

Monarch:10569 SLU7

NCBI Gene:10569 SLU7

OMIM:605974 SLU7

UCSC:O95391 SLU7

Reference Transcript

Other Identifiers

10569

11724469_at

11757348_s_at

17002402

227990_PM_at

227990_at

231718_PM_at

231718_at

2884659

2884660

2884661

2884663

2884664

2884666

2884667

2884669

2884671

2884673

2884674

2884675

2884676

2884678

2884679

2884680

2884682

2884683

2884684

2884688

43358_r_at

48520_at

52217_s_at

57018_at

8115606

A_23_P110704

A_24_P174824

A_24_P377328

GE79256

GE88616

GO:0000375

GO:0000380

GO:0000386

GO:0000389

GO:0000398

GO:0003723

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005737

GO:0005829

GO:0006397

GO:0006886

GO:0008270

GO:0008380

GO:0016020

GO:0016071

GO:0016607

GO:0030532

GO:0030628

GO:0034605

GO:0043226

GO:0043231

GO:0046872

GO:0065003

GO:0071013

GO:0140098

HMNXSV003044116

Hs.76325.0.A1_3p_at

Hs.76325.2.A1_3p_at

ILMN_1685369

PH_hs_0020409

TC05002010.hg

TC05003330.hg

Participates

as an input of

Formation of the Spliceosomal C* complex (Homo sapiens)

as a component of

as an output of

Inferred To

Slu7 [nucleoplasm] (Drosophila melanogaster)

Slu7 [nucleoplasm] (Mus musculus)

Slu7 [nucleoplasm] (Rattus norvegicus)

slu7 [nucleoplasm] (Danio rerio)

slu7 [nucleoplasm] (Dictyostelium discoideum)

slu7 [nucleoplasm] (Schizosaccharomyces pombe)

slu7 [nucleoplasm] (Xenopus tropicalis)

SLU7 [nucleoplasm] (Bos taurus)

SLU7 [nucleoplasm] (Canis familiaris)

SLU7 [nucleoplasm] (Sus scrofa)

hSLU7 [nucleoplasm] (Caenorhabditis elegans)

hSLU7 [nucleoplasm] (Gallus gallus)

hSLU7 [nucleoplasm] (Plasmodium falciparum)

Cross References

RefSeq

XP_011532720.1, NP_006416.3

OpenTargets

ENSG00000164609

GeneCards

O95391

HPA

ENSG00000164609-SLU7

Ensembl

ENSP00000297151, ENST00000297151, ENSG00000164609

PRO

O95391

Pharos - Targets

O95391

PDB

5XJC, 6ICZ, 7W5A, 8C6J, 6QDV, 7W5B

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H2H8 PPIL3	1	PPIL3 [nucleoplasm] (R-HSA-8952110)	0.801	7
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:Q9Y6K9 IKBKG	12	IKBKG D406V [cytosol] (R-HSA-5262943) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG [nucleoplasm] (R-HSA-4755413) K63polyUb-IKBKG [cytosol] (R-HSA-202530) Ub-285-IKBKG [cytosol] (R-HSA-741397) IKBKG [cytosol] (R-HSA-168108)	0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q9UBB4 ATX10			0.556	3
UniProt:Q13155 AIMP2	1	AIMP2 [cytosol] (R-HSA-379576)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q13643 FHL3			0.556	3
UniProt:P23508 CRCM			0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:Q96N21 AP4AT			0.556	3
UniProt:Q9NVV9 THAP1			0.556	3
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.556	3
UniProt:Q17RB8 LONRF1	1	LONRF1 [cytosol] (R-HSA-8850905)	0.556	3
UniProt:Q8NI38 IKBD			0.556	3
UniProt:Q4G0R1 Q4G0R1			0.556	3
UniProt:Q9H4E7 DEF6	1	DEF6 [cytosol] (R-HSA-9691487)	0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:P0DTD1-PRO_0000449629 REP			0.527	2
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.508	2
UniProt:Q13435 SF3B2	1	SF3B2 [nucleoplasm] (R-HSA-71971)	0.508	2
UniProt:O43395 PRPF3	1	PRPF3 [nucleoplasm] (R-HSA-6806806)	0.508	2
UniProt:Q9BZ95 NSD3	1	WHSC1L1 [nucleoplasm] (R-HSA-1183230)	0.508	2
UniProt:O75152 ZC3H11A	1	ZC3H11A [nucleoplasm] (R-HSA-8850659)	0.483	2

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