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RPS27A(77-156) [cytosol]
Stable Identifier
R-HSA-72363
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
40S small ribosomal protein 27A, 40S ribosomal protein S27a
Locations in the PathwayBrowser for interactor UniProt:Q6ICB0 DESI1
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Homo sapiens)
RPS27A(77-156) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62979 RPS27A
Gene Names
RPS27A, UBA80, UBCEP1
Chain
chain:1-76, chain:77-156
Reference Genes
BioGPS Gene:6233 RPS27A
COSMIC (genes):RPS27A RPS27A
CTD Gene:6233 RPS27A
dbSNP Gene:6233 RPS27A
ENSEMBL:ENSG00000143947 RPS27A
ENSEMBL_homo_sapiens_GENE:ENSG00000143947.15 RPS27A
HGNC:10417 RPS27A
KEGG Gene (Homo sapiens):6233 RPS27A
Monarch:6233 RPS27A
NCBI Gene:6233 RPS27A
OMIM:191343 RPS27A
UCSC:P62979 RPS27A
Reference Transcript
RefSeq:NM_002954.5 RPS27A
RefSeq:NM_001177413.1 RPS27A
RefSeq:NM_001135592.2 RPS27A
Other Identifiers
11741791_at
11744329_x_at
17119982
18670232
18670234
18670235
18670237
18670241
18670243
18670244
200017_PM_at
200017_at
242214_PM_at
242214_at
2482925
2482928
2482929
2482930
2482932
2482933
2482937
2482940
2482941
2482942
34570_at
3694166
3694168
3694170
3694172
6233
7893392
7893455
7893919
7894376
7894813
7894844
7908407
8001782
8042052
83250_at
A_23_P79732
GE716822
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005783
GO:0005789
GO:0005829
GO:0005840
GO:0005886
GO:0006412
GO:0010008
GO:0016020
GO:0016567
GO:0019941
GO:0022626
GO:0022627
GO:0030163
GO:0030666
GO:0031386
GO:0031410
GO:0031625
GO:0031982
GO:0032040
GO:0036211
GO:0043226
GO:0045202
GO:0046872
GO:0070062
GO:1990904
HMNXSV003033635
Hs.311640.0.A1_3p_at
Hs.328922.0.A1_3p_at
ILMN_2048326
S79522_at
TC01004921.hg
TC02000321.hg
g4506712_3p_at
g4506712_3p_x_at
Participates
as an output of
UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Homo sapiens)
as a component of
40S ribosomal complex [cytosol] (Homo sapiens)
Other forms of this molecule
RPS27A(1-76) [endocytic vesicle membrane]
RPS27A(77-156) [nucleoplasm]
Ub-33-RPS27A(1-76) [mitochondrial outer membrane]
Ub-63-RPS27A(1-76) [mitochondrial outer membrane]
Ub-6-RPS27A(1-76) [mitochondrial outer membrane]
Ub-11-RPS27A(1-76) [mitochondrial outer membrane]
Ub-48-RPS27A(1-76) [mitochondrial outer membrane]
Ub-29-RPS27A(1-76) [mitochondrial outer membrane]
Ub-27-RPS27A(1-76) [mitochondrial outer membrane]
N6-glycyl-L-lysine-RPS27A(1-76) [cytosol]
adenylatedlG76-RPS27A(1-76) [nucleoplasm]
RPS27A [cytosol]
adenylatedlG76-RPS27A(1-76) [cytosol]
Ub-48-RPS27A(1-76) [endoplasmic reticulum membrane]
Ub-48-RPS27A(1-76) [lysosomal membrane]
Ub-48-RPS27A(1-76) [endocytic vesicle membrane]
RPS27A(1-76) [endosome membrane]
RPS27A(1-76) [plasma membrane]
Ub-29-RPS27A(1-76) [cytosol]
Ub-6-RPS27A(1-76) [cytosol]
Ub-27-RPS27A(1-76) [cytosol]
Ub-33-RPS27A(1-76) [cytosol]
M1-RPS27A(1-76) [cytosol]
RPS27A(1-76) [endoplasmic reticulum membrane]
Ub-27-RPS27A(1-76) [nucleoplasm]
Ub-29-RPS27A(1-76) [nucleoplasm]
Ub-33-RPS27A(1-76) [nucleoplasm]
Ub-11-RPS27A(1-76) [nucleoplasm]
Ub-63-RPS27A(1-76) [endosome membrane]
Ub-63-RPS27A(1-76) [plasma membrane]
Ub-11-RPS27A(1-76) [cytosol]
RPS27A(1-76) [nucleoplasm]
Ub-48-RPS27A(1-76) [nucleoplasm]
Ub-63-RPS27A(1-76) [nucleoplasm]
Ub-6-RPS27A(1-76) [nucleoplasm]
RPS27A(1-76) [late endosome lumen]
RPS27A(1-76) [mitochondrial outer membrane]
Ub-48-RPS27A(1-76) [cytosol]
p-S65-RPS27A(1-76) [mitochondrial outer membrane]
RPS27A(1-76) [cytosol]
RPS27A(1-76) [lysosomal lumen]
Ub-63-RPS27A(1-76) [cytosol]
Inferred To
RPS27A [cytosol]
(Bos taurus)
RPS27A [cytosol]
(Canis familiaris)
RPS27A [cytosol]
(Gallus gallus)
RPS27A [cytosol]
(Sus scrofa)
RPS27A(77-156) [cytosol]
(Plasmodium falciparum)
rps27a [cytosol]
(Danio rerio)
rps27a [cytosol]
(Xenopus tropicalis)
Ghost homologue of RPS27A(77-156) [cytosol]
(Caenorhabditis elegans)
Ghost homologue of RPS27A(77-156) [cytosol]
(Saccharomyces cerevisiae)
Ghost homologue of RPS27A(77-156) [cytosol]
(Schizosaccharomyces pombe)
Rps27a [cytosol]
(Mus musculus)
Rps27a [cytosol]
(Rattus norvegicus)
ubqC [cytosol]
(Dictyostelium discoideum)
RpS27A [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002945.1
,
NP_001129064.1
,
NP_001170884.1
OpenTargets
ENSG00000143947
HPA
ENSG00000143947-RPS27A
GeneCards
P62979
Ensembl
ENST00000404735
,
ENSP00000272317
,
ENST00000402285
,
ENSG00000143947
,
ENSP00000383981
,
ENST00000272317
,
ENSP00000385659
PRO
P62979
Pharos - Targets
P62979
PDB
7F0N
,
3NHE
,
6Y57
,
6ZN5
,
6KIU
,
8OZ0
,
6OLZ
,
8G61
,
3VDZ
,
7R4X
,
6ZOL
,
7TQL
,
6Z6N
,
4R62
,
2L0T
,
8PPL
,
3N32
,
5FLX
,
8GLP
,
7WTX
,
5A2Q
,
7MQA
,
6XA1
,
8IVB
,
7A09
,
6ZMO
,
6G5I
,
5WVO
,
6ZMI
,
6OM7
,
8G6J
,
6ZP4
,
7WTZ
,
7QP6
,
6Z6M
,
7WTU
,
7WTT
,
6OLE
,
6Z6L
,
5YDK
,
7JQC
,
2KHW
,
8G5Y
,
6ZM7
,
7QP7
,
3PHD
,
7MQ9
,
3N30
,
8G60
,
2XK5
,
6SQS
,
7BWD
,
6G18
,
5AJ0
,
6KG6
,
6QZP
,
2L0F
,
2KWU
,
6DC6
,
6G53
,
3TBL
,
6Y0G
,
6IP6
,
6ZMT
,
5T2C
,
7XNY
,
6KFP
,
6SQO
,
6FEC
,
6ZVJ
,
6ZMW
,
6ZOJ
,
6J99
,
6KIW
,
6ZXF
,
3NOB
,
6OLG
,
2KTF
,
6ZON
,
8IFD
,
3K9P
,
6ZME
,
7WTW
,
6ZXE
,
3AXC
,
2KOX
,
4UG0
,
7OOJ
,
3PHW
,
6YBS
,
7WU0
,
6ZLW
,
7JQB
,
5LKS
,
8PPK
,
3I3T
,
6KIV
,
6ZXD
,
6IP8
,
4V6X
,
7WTV
,
6OLF
,
6ZVH
,
6ZUO
,
3NS8
,
6G5H
,
6OM0
,
6SQR
,
6G51
,
2KWV
,
6IP5
,
6ZXH
,
8T4S
,
6OLI
,
7K5I
,
6ZV6
,
6ZXG
,
8IFE
Interactors (38)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15038 DAZP2
0.781
9
UniProt:Q9Y3C5 RNF11
0.666
4
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.607
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:Q99732 LITAF
0.556
3
UniProt:Q9UHD9 UBQLN2
1
UBQLN2 [cytosol]
(R-HSA-8866007)
0.556
3
UniProt:Q9NRQ2 PLS4
0.556
3
UniProt:I6L9I8 I6L9I8
0.556
3
UniProt:Q8N3F0 MTURN
0.556
3
UniProt:Q96CS7 PKHB2
0.556
3
UniProt:Q13137 CACO2
0.556
3
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
UniProt:P54725 RAD23A
1
RAD23A [nucleoplasm]
(R-HSA-5688076)
0.556
3
UniProt:Q92567-2 FAM168A
0.556
3
UniProt:Q6ICB0 DESI1
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:Q9BXY0 MAK16
0.527
2
UniProt:Q9BSL1 UBAC1
1
UBAC1 [cytosol]
(R-HSA-8851644)
0.527
2
UniProt:Q6AW86 ZNF324B
1
ZNF324B [nucleoplasm]
(R-HSA-3323092)
0.527
2
UniProt:Q96H86 ZNF764
1
ZNF764 [nucleoplasm]
(R-HSA-3343766)
0.527
2
UniProt:O14978 ZNF263
1
ZNF263 [nucleoplasm]
(R-HSA-1027393)
0.527
2
UniProt:Q8N998 CCD89
0.527
2
UniProt:Q5VT40 FA78B
0.527
2
UniProt:P08311 CTSG
4
CTSG [azurophil granule lumen]
(R-HSA-6799137)
CTSG [cytosol]
(R-HSA-9635429)
CTSG [plasma membrane]
(R-HSA-538738)
CTSG [extracellular region]
(R-HSA-2228716)
0.527
2
UniProt:Q8TBF4 ZCRB1
2
ZCRB1 [cytosol]
(R-HSA-9682010)
ZCRB1 [nucleoplasm]
(R-HSA-6787853)
0.527
2
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
6
UniProt:Q9BT49 THAP7
0.527
2
UniProt:Q9NQZ8 ZNF71
1
ZNF71 [nucleoplasm]
(R-HSA-2454145)
0.527
2
UniProt:Q7RTS1 BHA15
0.527
2
UniProt:P08865 RPSA
2
RPSA [nucleoplasm]
(R-HSA-6798722)
RPSA [cytosol]
(R-HSA-72389)
0.527
2
UniProt:Q9H9D4 ZN408
0.527
2
UniProt:P21741 MDK
1
MDK [extracellular region]
(R-HSA-2160953)
0.527
2
UniProt:Q66K89 E4F1
0.527
2
UniProt:P49721 PSMB2
2
PSMB2 [nucleoplasm]
(R-HSA-174335)
PSMB2 [cytosol]
(R-HSA-68744)
0.527
2
UniProt:P16104 H2AFX
7
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
H2AFX [nucleoplasm]
(R-HSA-56151)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
H2AFX [extracellular region]
(R-HSA-977583)
0.527
3
UniProt:P18206 VCL
8
VCL(1-811)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713472)
VCL(1-811)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713480)
VCL(95 kDa) [cytosol]
(R-HSA-9861471)
VCL [specific granule lumen]
(R-HSA-6799711)
VCL [secretory granule lumen]
(R-HSA-6801010)
VCL [extracellular region]
(R-HSA-350736)
VCL [ficolin-1-rich granule lumen]
(R-HSA-6800985)
VCL [cytosol]
(R-HSA-350753)
0.527
2
UniProt:P15880 RPS2
3
RPS2 [nucleoplasm]
(R-HSA-6790655)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [cytosol]
(R-HSA-72347)
0.527
2
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