Reactome | RPLP0 [cytosol]

RPLP0 [cytosol]

Stable Identifier

R-HSA-72396

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

60S acidic ribosomal protein P0, L10E

Locations in the PathwayBrowser for interactor UniProt:Q9UHB9 SRP68

Expand all

Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Signaling by Interleukins (Homo sapiens)
    - Interleukin-12 family signaling (Homo sapiens)
      - Interleukin-12 signaling (Homo sapiens)
        
        Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)
        
        Expression of ribosomal protein lateral stalk subunit P0 (Homo sapiens)
        
        RPLP0 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P05388 RPLP0

Gene Names

RPLP0

Chain

chain:1-317

Reference Genes

BioGPS Gene:6175 RPLP0

COSMIC (genes):RPLP0 RPLP0

CTD Gene:6175 RPLP0

dbSNP Gene:6175 RPLP0

ENSEMBL:ENSG00000089157 RPLP0

HGNC:10371 RPLP0

KEGG:hsa:6175 RPLP0

Monarch:6175 RPLP0

NCBI Gene:6175 RPLP0

OMIM:180510 RPLP0

UCSC:P05388 RPLP0

Reference Transcript

Other Identifiers

11757772_x_at

16771216

201033_PM_x_at

201033_x_at

208856_PM_x_at

208856_x_at

211720_PM_x_at

211720_x_at

211972_PM_x_at

211972_x_at

214167_PM_s_at

214167_s_at

2477854

2477856

2477857

2477858

2477859

2477860

2477861

2477862

2477863

2477864

2477865

2477866

2477867

2839081

2839083

2839085

2839087

31538_at

3333094

3333101

3474345

3474346

3474347

3474348

3474349

3474350

3474351

3474352

3474353

3474354

3474355

3474356

3474357

3474358

3474359

3474360

3474361

3474362

3474363

3474364

3474365

3474366

3474367

3474368

3474369

3474370

3474371

57261_f_at

6175

7966996

8109750

A_23_P204472

A_32_P184796

GE55748

GO:0000027

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005829

GO:0005840

GO:0005925

GO:0006412

GO:0014069

GO:0016020

GO:0022625

GO:0022626

GO:0036464

GO:0042254

GO:0043226

GO:0065003

GO:0070062

GO:0070180

GO:0098794

GO:1990904

HMNXSV003019412

Hs.73742.3.A1_3p_s_at

ILMN_1709880

ILMN_1745075

ILMN_2402090

M17885_at

PH_hs_0030294

TC12002036.hg

g12653774_3p_s_at

Participates

as an output of

Expression of ribosomal protein lateral stalk subunit P0 (Homo sapiens)

as a component of

Inferred To

RpLP0 [cytosol] (Drosophila melanogaster)

rla-0 [cytosol] (Caenorhabditis elegans)

Ghost homologue of RPLP0 [cytosol] (Xenopus tropicalis)

RPLP0 [cytosol] (Bos taurus)

RPLP0 [cytosol] (Canis familiaris)

RPLP0 [cytosol] (Gallus gallus)

RPLP0 [cytosol] (Plasmodium falciparum)

RPLP0 [cytosol] (Sus scrofa)

RPP0 [cytosol] (Saccharomyces cerevisiae)

Rplp0 [cytosol] (Mus musculus)

Rplp0 [cytosol] (Rattus norvegicus)

rpp0 [cytosol] (Schizosaccharomyces pombe)

rplp0 [cytosol] (Danio rerio)

rplp0 [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_444505.1, NP_000993.1

OpenTargets

ENSG00000089157

ENSEMBL

ENSP00000376299, ENSP00000449328, ENST00000228306, ENST00000551150, ENSP00000366471, ENST00000392514, ENSP00000339027, ENST00000313104

HPA

ENSG00000089157-RPLP0

PRO

P05388

Pharos - Targets

P05388

GlyGen

P05388

PDB

4V6X, 6OLG, 8G5Z, 6ZME, 5AJ0, 8G60, 4V6W, 8G6J, 6ZMI, 6ZM7, 6ZMO

Interactors (37)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95793 STAU1			0.748	6
UniProt:O95273 CCDB1			0.742	7
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.69	4
UniProt:P26196 DDX6	1	DDX6 [cytosol] (R-HSA-430032)	0.623	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	20
UniProt:P05386 RPLP1	1	RPLP1 [cytosol] (R-HSA-72398)	0.564	4
UniProt:P05387 RPLP2	1	RPLP2 [cytosol] (R-HSA-72400)	0.564	4
UniProt:Q8N9T8 KRI1			0.547	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.527	5
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q12906 ILF3	3	ILF3 [nucleoplasm] (R-HSA-9760401) ILF3 [cytosol] (R-HSA-450564) p-T188,T315-ILF3 [cytosol] (R-HSA-9836381)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	3
UniProt:P62917 RPL8	3	RPL8 [cytosol] (R-HSA-72490) RPL8 [nucleoplasm] (R-HSA-9630985) 3OHH216-RPL8 [nucleoplasm] (R-HSA-9630976)	0.527	3
UniProt:P49711 CTCF	1	CTCF [nucleoplasm] (R-HSA-3782562)	0.527	3
UniProt:Q7RTS1 BHLHA15	1	BHLHA15 [nucleoplasm] (R-HSA-9922593)	0.527	2
UniProt:Q96LZ2 MAGBA			0.527	2
UniProt:Q5C9Z4 NOM1			0.527	3
UniProt:Q9P0M6 H2AW			0.527	2
UniProt:O76094 SRP72	1	SRP72 [cytosol] (R-HSA-265069)	0.527	2
UniProt:Q15050 RRS1			0.527	3
UniProt:P09989 RIPT			0.527	2
UniProt:P46779 RPL28	1	RPL28 [cytosol] (R-HSA-72444)	0.527	3
UniProt:Q14684 RRP1B			0.527	3
UniProt:P46777 RPL5	1	RPL5 [cytosol] (R-HSA-72482)	0.527	2
UniProt:Q9UHB9 SRP68	1	SRP68 [cytosol] (R-HSA-445234)	0.527	2
UniProt:P84098 RPL19	1	RPL19 [cytosol] (R-HSA-72424)	0.527	3
UniProt:P37108 SRP14	4	SRP14 [cytosol] (R-HSA-264941) SRP14 [ficolin-1-rich granule lumen] (R-HSA-6800439) SRP14 [extracellular region] (R-HSA-6806495) SRP14 [secretory granule lumen] (R-HSA-6800938)	0.527	2
UniProt:Q86VM9 ZCH18			0.527	2
UniProt:Q13283 G3BP1	1	G3BP1 [cytosol] (R-HSA-9729517)	0.527	2
UniProt:P42696 RBM34			0.527	4
UniProt:P36578 RPL4	1	RPL4 [cytosol] (R-HSA-72474)	0.527	3
UniProt:P13693 TCTP			0.527	2
UniProt:P62888 RPL30	1	RPL30 [cytosol] (R-HSA-72452)	0.527	3
UniProt:P61513 RPL37A	1	RPL37A [cytosol] (R-HSA-72468)	0.527	3
UniProt:P62753 RPS6	4	RPS6 [cytosol] (R-HSA-72381) p-5S-RPS6 [cytosol] (R-HSA-165727) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) RPS6 [nucleoplasm] (R-HSA-6790606)	0.483	3
UniProt:Q92731 ESR2	5	ESR2 [cytosol] (R-HSA-9020970) ESR2 [nucleoplasm] (R-HSA-446165) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) PalmS-ESR2 [cytosol] (R-HSA-9020979)	0.462	2

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