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eIF4E:4E-BP [cytosol]
Stable Identifier
R-HSA-72581
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
Cap-dependent Translation Initiation (Homo sapiens)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Homo sapiens)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Homo sapiens)
eIF4E:4E-BP [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
MTOR signalling (Homo sapiens)
mTORC1-mediated signalling (Homo sapiens)
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
eIF4E:4E-BP [cytosol] (Homo sapiens)
Participants
components
EIF4E [cytosol]
(Homo sapiens)
EIF4EBP1 [cytosol]
(Homo sapiens)
Participates
as an input of
Release of eIF4E from the inactive eIF4E:4E-BP complex (Homo sapiens)
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
Inferred To
eIF4E:4E-BP [cytosol]
(Bos taurus)
eIF4E:4E-BP [cytosol]
(Canis familiaris)
eIF4E:4E-BP [cytosol]
(Danio rerio)
eIF4E:4E-BP [cytosol]
(Dictyostelium discoideum)
eIF4E:4E-BP [cytosol]
(Drosophila melanogaster)
eIF4E:4E-BP [cytosol]
(Gallus gallus)
eIF4E:4E-BP [cytosol]
(Mus musculus)
eIF4E:4E-BP [cytosol]
(Rattus norvegicus)
eIF4E:4E-BP [cytosol]
(Sus scrofa)
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