Cap-bound mRNA is activated by helicases

Stable Identifier
R-HSA-72647
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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The DEAD-box RNA helicase eIF4A, together with the RNA-binding proteins eIF4B or eIF4H, is thought to unwind RNA secondary structures near the 5'-end of the mRNA and in the presence of ATP.

Literature References
PubMed ID Title Journal Year
6853548 New initiation factor activity required for globin mRNA translation.

Grifo, JA, Tahara, SM, Morgan, MA, Shatkin, AJ, Merrick, WC

J Biol Chem 1983
Participants
Participates
Catalyst Activity

RNA helicase activity of eIF4A subunits complex [cytosol]

Orthologous Events
Created
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