Met-tRNAi binds to eIF2:GTP to form the ternary complex

Stable Identifier
R-HSA-72669
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Met-tRNAi binds to eIF2:GTP to form the ternary complex
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The ternary complex forms upon binding of the initiator methionyl-tRNA to the active eIF2:GTP complex.
Literature References
PubMed ID Title Journal Year
1104615 Binding of MET-TRNAf and GTP to homogeneous initiation factor MP.

Anderson, WF, Safer, B, Adams, SL, Merrick, WC

J Biol Chem 1976
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This event is regulated
Requirements
Orthologous Events
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Bos taurus)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Caenorhabditis elegans)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Canis familiaris)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Danio rerio)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Dictyostelium discoideum)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Drosophila melanogaster)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Gallus gallus)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Mus musculus)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Plasmodium falciparum)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Rattus norvegicus)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Saccharomyces cerevisiae)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Schizosaccharomyces pombe)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Sus scrofa)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Xenopus tropicalis)
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