eIF2 activation

Stable Identifier
R-HSA-72722
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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eIF2 activation
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eIF2B is a guanine nucleotide releasing factor that is required to cause GDP release so that a new GTP molecule can bind and activate eIF2, so that it can be reused.
Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

translation initiation factor activity of eIF2B subunits complex [cytosol]

Physical Entity
eIF2B subunits complex [cytosol] (Homo sapiens)
Activity
translation initiation factor activity (GO:0003743)
Orthologous Events
eIF2 activation (Bos taurus)
eIF2 activation (Caenorhabditis elegans)
eIF2 activation (Canis familiaris)
eIF2 activation (Danio rerio)
eIF2 activation (Dictyostelium discoideum)
eIF2 activation (Drosophila melanogaster)
eIF2 activation (Gallus gallus)
eIF2 activation (Mus musculus)
eIF2 activation (Plasmodium falciparum)
eIF2 activation (Rattus norvegicus)
eIF2 activation (Saccharomyces cerevisiae)
eIF2 activation (Schizosaccharomyces pombe)
eIF2 activation (Sus scrofa)
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