dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]

Stable Identifier
R-HSA-73635
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
Synonyms
phosphorylation of dUMP or TMP to dUDP or TDP
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dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]
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Cytosolic deoxythymidylate kinase (DTYMK) catalyzes the reversible reaction of either dUMP or TMP with ATP to form dUDP or TDP. The active form of the enzyme is a homodimer (Lee and Cheng 1977).

Literature References
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Output
Participates
as an event of
Catalyst Activity

nucleoside monophosphate kinase activity of DTYMK dimer [cytosol]

Physical Entity
DTYMK dimer [cytosol] (Homo sapiens)
Activity
nucleoside monophosphate kinase activity (GO:0050145)
Orthologous Events
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Bos taurus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Canis familiaris)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Danio rerio)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Gallus gallus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Mus musculus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Rattus norvegicus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Sus scrofa)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Xenopus tropicalis)
Cross References
Rhea
Created
Jassal, B  (2003-06-17)
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