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RNA Polymerase II Promoter Escape
Stable Identifier
R-HSA-73776
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)
RNA Polymerase II Promoter Escape (Homo sapiens)
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RNA Polymerase II promoter escape occurs after the first phosphodiester bond has been created.
Literature References
PubMed ID
Title
Journal
Year
9405375
Three transitions in the RNA polymerase II transcription complex during initiation.
Fiedler, U
,
Timmers, HT
,
Holstege, FC
EMBO J
1998
Participants
Events
Unwinding DNA for the nascent transcript
(Homo sapiens)
Addition of the third nucleotide on the nascent transcript
(Homo sapiens)
Unwinding of DNA for the Nascent Transcript: Second Transition
(Homo sapiens)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition
(Homo sapiens)
Addition of Nucleotides 5 through 9 on the growing Transcript
(Homo sapiens)
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition
(Homo sapiens)
Addition of nucleotides between position +11 and +30
(Homo sapiens)
Participates
as an event of
RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)
Event Information
Go Biological Process
transcription elongation by RNA polymerase II (0006368)
Orthologous Events
RNA Polymerase II Promoter Escape (Bos taurus)
RNA Polymerase II Promoter Escape (Caenorhabditis elegans)
RNA Polymerase II Promoter Escape (Canis familiaris)
RNA Polymerase II Promoter Escape (Dictyostelium discoideum)
RNA Polymerase II Promoter Escape (Drosophila melanogaster)
RNA Polymerase II Promoter Escape (Gallus gallus)
RNA Polymerase II Promoter Escape (Mus musculus)
RNA Polymerase II Promoter Escape (Plasmodium falciparum)
RNA Polymerase II Promoter Escape (Rattus norvegicus)
RNA Polymerase II Promoter Escape (Saccharomyces cerevisiae)
RNA Polymerase II Promoter Escape (Schizosaccharomyces pombe)
RNA Polymerase II Promoter Escape (Sus scrofa)
RNA Polymerase II Promoter Escape (Xenopus tropicalis)
RNA Polymerase II HIV Promoter Escape (Homo sapiens)
Authored
Timmers, HTM (2003-09-11)
Created
Timmers, HTM (2003-09-11)
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