Base-Excision Repair, AP Site Formation

Stable Identifier
R-HSA-73929
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Base-Excision Repair, AP Site Formation
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Base excision repair is initiated by DNA glycosylases that hydrolytically cleave the base-deoxyribose glycosyl bond of a damaged nucleotide residue, releasing the damaged base (Lindahl and Wood 1999, Sokhansanj et al. 2002).
Literature References
PubMed ID Title Journal Year
11937636 A quantitative model of human DNA base excision repair. I. Mechanistic insights

Fitch, JP, Sokhansanj, BA, Rodrigue, GR, Wilson DM, 3rd

Nucleic Acids Res 2002
10583946 Quality control by DNA repair

Lindahl, T, Wood, RD

Science 1999
Participants
Events
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as an event of
Event Information
Go Biological Process
base-excision repair, AP site formation (0006285)
Orthologous Events
Base-Excision Repair, AP Site Formation (Bos taurus)
Base-Excision Repair, AP Site Formation (Caenorhabditis elegans)
Base-Excision Repair, AP Site Formation (Canis familiaris)
Base-Excision Repair, AP Site Formation (Danio rerio)
Base-Excision Repair, AP Site Formation (Dictyostelium discoideum)
Base-Excision Repair, AP Site Formation (Drosophila melanogaster)
Base-Excision Repair, AP Site Formation (Gallus gallus)
Base-Excision Repair, AP Site Formation (Mus musculus)
Base-Excision Repair, AP Site Formation (Plasmodium falciparum)
Base-Excision Repair, AP Site Formation (Rattus norvegicus)
Base-Excision Repair, AP Site Formation (Saccharomyces cerevisiae)
Base-Excision Repair, AP Site Formation (Schizosaccharomyces pombe)
Base-Excision Repair, AP Site Formation (Sus scrofa)
Base-Excision Repair, AP Site Formation (Xenopus tropicalis)
Authored
Matthews, L  (2004-02-03)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Matthews, L  (2004-02-03)
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