Insulin receptor [plasma membrane]

Stable Identifier
R-HSA-74675
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
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General
The human insulin receptor is expressed as two isoforms that are generated by alternate splicing of its mRNA; the B isoform has 12 additional amino acids (718-729) encoded by exon 11 of the gene.
Literature References
PubMed ID Title Journal Year
2983222 Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes.

Bell, JR, Chen, EY, Ullrich, A, Tsubokawa, M, Coussens, L, Liao, YC, Dull, TJ, Gray, A, Herrera, R, Petruzzelli, LM

Nature 1985
2859121 The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling.

Masiarz, F, Kan, YW, Clauser, E, Ou, JH, Edery, M, Graf, L, Ellis, L, Jarnagin, K, Ebina, Y, Goldfine, ID

Cell 1985
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components
Participates
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Inferred To
Insulin receptor [plasma membrane] (Bos taurus)
Insulin receptor [plasma membrane] (Caenorhabditis elegans)
Insulin receptor [plasma membrane] (Canis familiaris)
Insulin receptor [plasma membrane] (Danio rerio)
Insulin receptor [plasma membrane] (Drosophila melanogaster)
Insulin receptor [plasma membrane] (Gallus gallus)
Insulin receptor [plasma membrane] (Mus musculus)
Insulin receptor [plasma membrane] (Rattus norvegicus)
Insulin receptor [plasma membrane] (Sus scrofa)
Insulin receptor [plasma membrane] (Xenopus tropicalis)
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