Signal attenuation

Stable Identifier
R-HSA-74749
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Signal attenuation
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Now with the complete receptor-ligand dissociation and subsequent degradation of insulin in the endosomal lumen, the endosomally associated protein tyrosine phosphatases (PTPs) complete the receptor dephosphorylation. So too are all the receptor substrates dephosphorylated leading to the collapse of the signalling complexes and signal attenuation.
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Orthologous Events
Signal attenuation (Bos taurus)
Signal attenuation (Canis familiaris)
Signal attenuation (Danio rerio)
Signal attenuation (Drosophila melanogaster)
Signal attenuation (Gallus gallus)
Signal attenuation (Mus musculus)
Signal attenuation (Rattus norvegicus)
Signal attenuation (Sus scrofa)
Signal attenuation (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Created
Bevan, AP  (2003-07-31)
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