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Sal Box [nucleoplasm]
Stable Identifier
R-HSA-74975
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 (Homo sapiens)
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
NoRC:HDAC:DNMT methylates cytosine of the rRNA genes (Homo sapiens)
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA (Homo sapiens)
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I binds to the Sal Box (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
Positive epigenetic regulation of rRNA expression (Homo sapiens)
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression (Homo sapiens)
Recruitment of ERCC6 (CSB), EHMT2 (G9a), and NuRD to the promoter of rRNA gene (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I binds to the Sal Box (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9 (Homo sapiens)
TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Homo sapiens)
TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Termination (Homo sapiens)
Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I binds to the Sal Box (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
Sal Box [nucleoplasm] (Homo sapiens)
General
Named the "Sal Box" as a Sal I restriction endonuclease site is located within the sequence. An 18 base pair sequence element found in multiple copies in the nontranscribed spacer downstream of the 18S rRNA coding region. This element provides the termination signal for ribosomal gene transcription.
External Reference Information
External Reference
NCBI Nucleotide:U13369 45S pre-rRNA gene
Gene Names
45S pre-rRNA gene
Participates
as a component of
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
as an input of
TTF-I binds to the Sal Box (Homo sapiens)
Inferred To
Ghost homologue of Sal Box [nucleoplasm]
(Bos taurus)
Ghost homologue of Sal Box [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of Sal Box [nucleoplasm]
(Canis familiaris)
Ghost homologue of Sal Box [nucleoplasm]
(Gallus gallus)
Ghost homologue of Sal Box [nucleoplasm]
(Mus musculus)
Ghost homologue of Sal Box [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of Sal Box [nucleoplasm]
(Sus scrofa)
Ghost homologue of Sal Box [nucleoplasm]
(Xenopus tropicalis)
Cross References
NCBI Nucleotide
U13369
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