Elongation of pre-rRNA transcript

Stable Identifier
R-HSA-74986
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleolus
ReviewStatus
5/5
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Elongation of pre-rRNA transcript
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'elongating pre-rRNA transcript', and 1 molecule of 'NTP' are present. At the end of this reaction, 1 molecule of 'elongating pre-rRNA transcript' is present.

This reaction takes place in the 'nucleolus' and is mediated by the 'DNA-directed RNA polymerase activity' of 'RNA Polymerase I promoter escape complex'.
Literature References
PubMed ID Title Journal Year
14969726 Mechanism of RNA polymerase I transcription

Comai, L

Adv. Protein Chem. 2004
Participants
Input
Output
Participates
as an event of
Catalyst Activity

DNA-directed RNA polymerase activity of RNA Polymerase I promoter escape complex [nucleoplasm]

Physical Entity
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Activity
DNA-directed RNA polymerase activity (GO:0003899)
This event is regulated
Positively by
Regulator
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Homo sapiens)
Orthologous Events
Elongation of pre-rRNA transcript (Bos taurus)
Elongation of pre-rRNA transcript (Caenorhabditis elegans)
Elongation of pre-rRNA transcript (Canis familiaris)
Elongation of pre-rRNA transcript (Dictyostelium discoideum)
Elongation of pre-rRNA transcript (Drosophila melanogaster)
Elongation of pre-rRNA transcript (Gallus gallus)
Elongation of pre-rRNA transcript (Mus musculus)
Elongation of pre-rRNA transcript (Rattus norvegicus)
Elongation of pre-rRNA transcript (Saccharomyces cerevisiae)
Elongation of pre-rRNA transcript (Schizosaccharomyces pombe)
Elongation of pre-rRNA transcript (Sus scrofa)
Elongation of pre-rRNA transcript (Xenopus tropicalis)
Created
Comai, L  (2003-07-03)
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