At the beginning of this reaction, 1 molecule of 'Cyclin D1:Cdk4', and 1 molecule of 'ATP' are present. At the end of this reaction, 1 molecule of 'phospho(T286)-Cyclin D1:Cdk4', and 1 molecule of 'ADP' are present. This reaction takes place in the 'nucleus' and is mediated by the 'kinase activity' of 'glycogen synthase kinase-3 beta'.
Herman, JG, Barbash, O, Lu, F, Zhang, F, Benzeno, S, Klein, PS, Diehl, JA, Guo, M, Rustgi, A
protein serine/threonine kinase activity of GSK3B [nucleoplasm]
© 2023 Reactome