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Newly Formed Phosphodiester Bond Stabilized and PPi Released
Stable Identifier
R-HSA-75864
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)
RNA Polymerase II Transcription Initiation (Homo sapiens)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'Pol II Initiation complex with phosphodiester-PPi intermediate' is present. At the end of this reaction, 1 molecule of 'pyrophosphate', and 1 molecule of 'pol II transcription complex' are present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
9405375
Three transitions in the RNA polymerase II transcription complex during initiation.
Fiedler, U
,
Timmers, HT
,
Holstege, FC
EMBO J
1998
Participants
Input
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm]
(Homo sapiens)
Output
pol II transcription complex [nucleoplasm]
(Homo sapiens)
PPi [nucleoplasm]
Participates
as an event of
RNA Polymerase II Transcription Initiation (Homo sapiens)
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Created
Timmers, HTM (2003-09-11)
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