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Abortive Initiation After Second Transition
Stable Identifier
R-HSA-75891
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Abortive Initiation After Second Transition (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'pol II transcription complex containing 4-9 nucleotide long transcript' is present. At the end of this reaction, 1 molecule of 'template DNA:4-9 nucleotide transcript hybrid', 1 molecule of 'TFIIH', 1 molecule of 'TFIIE', and 1 molecule of 'RNA Polymerase II (unphosphorylated):TFIIF complex' are present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
1939271
Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.
Luse, SW
,
Jacob, GA
,
Luse, DS
J Biol Chem
1991
Participants
Input
pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm]
(Homo sapiens)
Output
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
(Homo sapiens)
template DNA:4-9 nucleotide transcript hybrid [nucleoplasm]
TFIIE [nucleoplasm]
(Homo sapiens)
TFIIH [nucleoplasm]
(Homo sapiens)
Participates
as an event of
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Orthologous Events
Abortive HIV-1 Initiation After Second Transition (Homo sapiens)
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Abortive Initiation After Second Transition (Canis familiaris)
Abortive Initiation After Second Transition (Dictyostelium discoideum)
Abortive Initiation After Second Transition (Drosophila melanogaster)
Abortive Initiation After Second Transition (Gallus gallus)
Abortive Initiation After Second Transition (Mus musculus)
Abortive Initiation After Second Transition (Rattus norvegicus)
Abortive Initiation After Second Transition (Saccharomyces cerevisiae)
Abortive Initiation After Second Transition (Schizosaccharomyces pombe)
Abortive Initiation After Second Transition (Sus scrofa)
Abortive Initiation After Second Transition (Xenopus tropicalis)
Created
Timmers, HTM (2003-09-11)
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