1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]

Stable Identifier
R-HSA-75900
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Conversion of Diacylglycerol to Triacylglycerol [DGAT1]
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Tetrameric diacylglycerol O-acyltransferase 1 (DGAT1) associated with the endoplasmic reticulum membrane catalyzes the reaction of 1,2-diacyl-glycerol and acyl-CoA to form triacylglycerol + CoASH (Cheng et al. 2001).

Literature References
PubMed ID Title Journal Year
11672446 Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein

Cheng, D, Meegalla, RL, He, B, Cromley, DA, Billheimer, JT, Young, PR

Biochem J 2001
Participants
Participates
Catalyst Activity

diacylglycerol O-acyltransferase activity of DGAT1 tetramer [endoplasmic reticulum membrane]

Orthologous Events
Created
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