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FASL:FAS Receptor monomer [plasma membrane]
Stable Identifier
R-HSA-76564
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)
Caspase activation via Death Receptors in the presence of ligand (Homo sapiens)
Caspase-8 processing in the DISC (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
DISC:procaspase-8-dimer [plasma membrane] (Homo sapiens)
FASL:FAS receptor trimer:FADD:procaspase-8-dimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Dimerization of procaspase-8 (Homo sapiens)
FAS-mediated dimerization of procaspase-8 (Homo sapiens)
FASL:FAS receptor trimer:FADD:procaspase-8-dimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Regulation by c-FLIP (Homo sapiens)
Caspase-8 and FLIP(L) processing at DISC (Homo sapiens)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Homo sapiens)
FASL:FAS Receptor Trimer:FADD:pro-Caspase-8:FLIP(L) [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Regulated Necrosis (Homo sapiens)
RIPK1-mediated regulated necrosis (Homo sapiens)
RIPK3 binds RIPK1 (Homo sapiens)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Regulation of necroptotic cell death (Homo sapiens)
CASP8 activity is inhibited (Homo sapiens)
FLIP(L) and procaspase-8 form heterodimer (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FLIP(S) and procaspase-8 form heterodimer (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Homo sapiens)
DISC:procaspase-8 [plasma membrane] (Homo sapiens)
DISC [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
FasL/ CD95L signaling (Homo sapiens)
FASL binds FAS Receptor (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD:pro-Caspase-10 [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FasL:Fas binds FADD (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Trimerization of the FASL:FAS receptor complex (Homo sapiens)
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
FASL:FAS Receptor monomer [plasma membrane] (Homo sapiens)
Participants
components
FAS [plasma membrane]
(Homo sapiens)
FASLG(1-281) [extracellular region]
(Homo sapiens)
Participates
as an output of
FASL binds FAS Receptor (Homo sapiens)
as an input of
Trimerization of the FASL:FAS receptor complex (Homo sapiens)
as a component of
FASL:FAS Receptor Trimer [plasma membrane] (Homo sapiens)
Inferred To
FASL:FAS Receptor monomer [plasma membrane]
(Bos taurus)
FASL:FAS Receptor monomer [plasma membrane]
(Canis familiaris)
FASL:FAS Receptor monomer [plasma membrane]
(Gallus gallus)
FASL:FAS Receptor monomer [plasma membrane]
(Mus musculus)
FASL:FAS Receptor monomer [plasma membrane]
(Rattus norvegicus)
FASL:FAS Receptor monomer [plasma membrane]
(Sus scrofa)
FASL:FAS Receptor monomer [plasma membrane]
(Xenopus tropicalis)
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