Formation of cap binding complex (CBC)

Stable Identifier
R-HSA-77094
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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At the beginning of this reaction, 1 molecule of 'CBP80', and 1 molecule of 'CBP20' are present. At the end of this reaction, 1 molecule of 'Cap Binding Complex (CBC)' is present (Glover-Cutter et al., 2008, Görnemann et al., 2005, Narita et al., 2007). This reaction takes place in the nucleus.

Literature References
PubMed ID Title Journal Year
18157150 RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes

Kim, S, Espinosa, J, Bentley, DL, Glover-Cutter, K

Nat. Struct. Mol. Biol. 2008
15989964 Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex

Neugebauer, KM, Hujer, K, Kotovic, KM, Görnemann, J

Mol. Cell 2005
17499042 NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs

Tanaka, K, Tanabe, H, Handa, H, Yung, TM, Narita, T, Yamaguchi, Y, Tsuboi, Y, Yamamoto, J

Mol. Cell 2007
28297668 Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate

Schulze, WM, Giacometti, S, Kudla, G, Bertrand, E, Verheggen, C, Meola, N, Robert, MC, Lubas, M, Andersen, JS, Bukenborg, J, Jensen, TH, Benbahouche, NE, Domanski, M

Cell Rep 2017
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