3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA

Stable Identifier
R-HSA-77309
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of '3-Oxododecanoyl-CoA', and 1 molecule of 'CoA' are present. At the end of this reaction, 1 molecule of 'Decanoyl-CoA', and 1 molecule of 'Acetyl-CoA' are present.

This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'transferase activity' of 'Trifunctional Protein'.
Literature References
PubMed ID Title Journal Year
1550553 Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria.

Carpenter, K, Pollitt, RJ, Middleton, B

Biochem Biophys Res Commun 1992
Participants
Input
Output
Participates
as an event of
Catalyst Activity

acetyl-CoA C-acyltransferase activity of Trifunctional Protein [mitochondrial matrix]

Physical Entity
Trifunctional Protein [mitochondrial matrix] (Homo sapiens)
Activity
acetyl-CoA C-acyltransferase activity (GO:0003988)
Orthologous Events
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Bos taurus)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Caenorhabditis elegans)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Canis familiaris)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Danio rerio)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Drosophila melanogaster)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Gallus gallus)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Mus musculus)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Rattus norvegicus)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Sus scrofa)
3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA (Xenopus tropicalis)
Cross References
RHEA
Created
Gillespie, ME  (2003-09-19)
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