Cleavage of Intronless Pre-mRNA at 3'-end

Stable Identifier
R-HSA-77592
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Cleavage of Intronless Pre-mRNA at 3'-end
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The polypeptide catalyzing the hydrolysis of the phosphodiester bond remains to be identified. Cleavage produces a 3'-OH on the upstream fragment and a 5'-phosphate on the downstream fragment. At some unknown point after cleavage, the downstream fragment, CstF, CF I and CF II are thought to be released, whereas CPSF and poly(A) polymerase remain to carry out polyadenylation.
Participants
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Output
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as an event of
Orthologous Events
Cleavage of Intronless Pre-mRNA at 3'-end (Bos taurus)
Cleavage of Intronless Pre-mRNA at 3'-end (Caenorhabditis elegans)
Cleavage of Intronless Pre-mRNA at 3'-end (Canis familiaris)
Cleavage of Intronless Pre-mRNA at 3'-end (Drosophila melanogaster)
Cleavage of Intronless Pre-mRNA at 3'-end (Gallus gallus)
Cleavage of Intronless Pre-mRNA at 3'-end (Mus musculus)
Cleavage of Intronless Pre-mRNA at 3'-end (Rattus norvegicus)
Cleavage of Intronless Pre-mRNA at 3'-end (Sus scrofa)
Authored
Wahle, E  (2003-06-05)
Created
Wahle, E  (2003-06-05)
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