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Binding of ADAR2 homodimer to dsRNA duplex
Stable Identifier
R-HSA-77613
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism of RNA (Homo sapiens)
mRNA Editing (Homo sapiens)
mRNA Editing: A to I Conversion (Homo sapiens)
Formation of editosomes by ADAR proteins (Homo sapiens)
Binding of ADAR2 homodimer to dsRNA duplex (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'dsRNA duplex', and 1 molecule of 'ADAR2 homodimer' are present. At the end of this reaction, 1 molecule of 'Editosome (ADAR2) complex' is present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
9149227
Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette
Keller, W
,
Gerber, A
,
O'Connell, MA
RNA
1997
Participants
Input
ADAR2 homodimer [nucleoplasm]
(Homo sapiens)
dsRNA duplex [nucleoplasm]
Output
Editosome (ADAR2) complex [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Formation of editosomes by ADAR proteins (Homo sapiens)
Orthologous Events
Binding of ADAR2 homodimer to dsRNA duplex (Bos taurus)
Binding of ADAR2 homodimer to dsRNA duplex (Caenorhabditis elegans)
Binding of ADAR2 homodimer to dsRNA duplex (Canis familiaris)
Binding of ADAR2 homodimer to dsRNA duplex (Drosophila melanogaster)
Binding of ADAR2 homodimer to dsRNA duplex (Mus musculus)
Binding of ADAR2 homodimer to dsRNA duplex (Rattus norvegicus)
Binding of ADAR2 homodimer to dsRNA duplex (Sus scrofa)
Binding of ADAR2 homodimer to dsRNA duplex (Xenopus tropicalis)
Created
Carmichael, GG (2003-12-05)
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