HSD17B1 hydrogenates E1 to EST17b

Stable Identifier
R-HSA-804969
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Estrone is hydrogenated to estradiol
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Expression of HSD17B1 which is the main enzyme that catalyzes the hydrogenation of estrone is strongly restricted to placenta, ovaries, endometrium and breast tissue (Moeller and Adamski, 2009).

Literature References
PubMed ID Title Journal Year
19027824 Integrated view on 17beta-hydroxysteroid dehydrogenases

Moeller, G, Adamski, J

Mol Cell Endocrinol. 2009
Participants
Participates
Event Information
Catalyst Activity

estradiol 17-beta-dehydrogenase activity of HSD17B1 dimer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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