FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8

Stable Identifier
R-HSA-83586
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8
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Caspase-8 precursor (Pro-Caspase-8, also known as MACH) binds the complex of FADD and FASL:FAS receptor trimer (Boldin et al. 1996).

Literature References
PubMed ID Title Journal Year
8681376 Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

Wallach, D, Goncharov, TM, Boldin, MP, Goltsev, YV

Cell 1996
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Orthologous Events
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Bos taurus)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Danio rerio)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Gallus gallus)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Mus musculus)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Rattus norvegicus)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Sus scrofa)
Authored
Gillespie, ME  (2004-08-24)
Reviewed
Salvesen, GS  (2013-05-22)
Pop, C  (2013-05-22)
Created
Tschopp, J  (2004-01-28)
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